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Knockdown of P2Y4 ameliorates sepsis-induced acute kidney injury in mice via inhibiting the activation of the NF-κB/MMP8 axis

Sepsis-induced acute kidney injury (S-AKI) has emerged as a frequent and life-threatening complication in critically ill patients, which is characterized by a systematic inflammatory response and a rapid decline in kidney function. P2Y4, a member of G protein–coupled P2Y nucleotide receptor family,...

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Detalles Bibliográficos
Autores principales:	Wang, Maojuan, Jiang, Fan, Zhang, Lian, Zhang, Juan, Xie, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467379/ https://www.ncbi.nlm.nih.gov/pubmed/36105291 http://dx.doi.org/10.3389/fphys.2022.953977

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