LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis

Objective: Extensive studies have shown that ERS may be implicated in the pathogenesis of DCM. We explored the therapeutic effects of lncRNAH19 on DCM and its effect on ERS-associated cardiomyocyte apoptosis. Methods: C57/BL-6j mice were randomly divided into 3 groups: non-DM group (controls), DM gr...

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Detalles Bibliográficos
Autores principales: Wang, Sixuan, Duan, Jun, Liao, Jiangquan, Wang, Yan, Xiao, Xiang, Li, Lin, Liu, Yi, Gu, Huan, Yang, Peng, Fu, Dongliang, Du, Jinhang, Li, Xianlun, Shao, Mingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467416/
https://www.ncbi.nlm.nih.gov/pubmed/36044268
http://dx.doi.org/10.18632/aging.204256

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