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Prior Diagnosis of COVID Has No Increased Complications in Total Joint Arthroplasty

Introduction Although a substantial portion of the United States population has been infected with and recovered from Coronavirus Disease-19 (COVID-19), many patients may have persistent symptoms and complications from disease-driven respiratory disease, arrhythmias, and venous thromboembolism (VTE)...

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Autores principales: Lung, Brandon E, Taka, Taha M, Donnelly, Megan, McLellan, Maddison, Callan, Kylie, Issagholian, Leo, Lai, Wilson, So, David, McMaster, William, Yang, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467498/
https://www.ncbi.nlm.nih.gov/pubmed/36120273
http://dx.doi.org/10.7759/cureus.27974
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author Lung, Brandon E
Taka, Taha M
Donnelly, Megan
McLellan, Maddison
Callan, Kylie
Issagholian, Leo
Lai, Wilson
So, David
McMaster, William
Yang, Steven
author_facet Lung, Brandon E
Taka, Taha M
Donnelly, Megan
McLellan, Maddison
Callan, Kylie
Issagholian, Leo
Lai, Wilson
So, David
McMaster, William
Yang, Steven
author_sort Lung, Brandon E
collection PubMed
description Introduction Although a substantial portion of the United States population has been infected with and recovered from Coronavirus Disease-19 (COVID-19), many patients may have persistent symptoms and complications from disease-driven respiratory disease, arrhythmias, and venous thromboembolism (VTE). With institutions resuming elective total joint arthroplasties (TJA), it is unclear whether a prior resolved diagnosis of COVID has any implications on postoperative outcomes. Methods All elective TJA performed in 2021 at our institution were retrospectively reviewed and a history of prior COVID+ result recorded. Baseline demographics, days from prior COVID+ result to surgery date, preoperative methicillin-resistant Staphylococcus aureus (MRSA) nares colonization, and laboratory markers were obtained to determine baseline characteristics. Postoperative estimated blood loss (EBL), length of stay (LOS), rate of revision surgery, and discharge destination were compared between groups. Perioperative and postoperative rates of VTE, urinary tract infection (UTI), pneumonia, postoperative oxygen supplementation, cardiac arrhythmia, renal disease, sepsis, and periprosthetic joint infections within six months of surgery were recorded. Results Of the 155 elective TJA performed in 2021, 24 patients had a prior COVID+ diagnosis with a mean of 253 days from positive result to surgery date. There were no significant differences in baseline demographics, comorbidities, and preoperative lab markers between groups. Surgeries on patients with a prior COVID+ had a significantly higher EBL (260 vs 175cc), but postoperative outcomes of VTE, UTI, pneumonia, oxygen supplementation requirement, nares MRSA+, cardiac disease, and infection rates between groups were similar. Bivariate logistic regression revealed increased days from COVID+ diagnosis (>6 months) to surgery date were associated with a shorter LOS. Conclusion Although a prior COVID+ diagnosis had increased intraoperative blood loss, there were no significant differences in respiratory, infectious, cardiac, and thromboembolic complications up to six months after elective TJA. This study suggests that asymptomatic C+ patients receiving elective TJA do not require more aggressive prophylactic anticoagulation or antibiotic regimens to prevent VTE or perioperative infections. As institutions around the nation resume pre-COVID rates of arthroplasty surgeries, a prior diagnosis of COVID appears to have no effects on postoperative complications.
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spelling pubmed-94674982022-09-15 Prior Diagnosis of COVID Has No Increased Complications in Total Joint Arthroplasty Lung, Brandon E Taka, Taha M Donnelly, Megan McLellan, Maddison Callan, Kylie Issagholian, Leo Lai, Wilson So, David McMaster, William Yang, Steven Cureus Orthopedics Introduction Although a substantial portion of the United States population has been infected with and recovered from Coronavirus Disease-19 (COVID-19), many patients may have persistent symptoms and complications from disease-driven respiratory disease, arrhythmias, and venous thromboembolism (VTE). With institutions resuming elective total joint arthroplasties (TJA), it is unclear whether a prior resolved diagnosis of COVID has any implications on postoperative outcomes. Methods All elective TJA performed in 2021 at our institution were retrospectively reviewed and a history of prior COVID+ result recorded. Baseline demographics, days from prior COVID+ result to surgery date, preoperative methicillin-resistant Staphylococcus aureus (MRSA) nares colonization, and laboratory markers were obtained to determine baseline characteristics. Postoperative estimated blood loss (EBL), length of stay (LOS), rate of revision surgery, and discharge destination were compared between groups. Perioperative and postoperative rates of VTE, urinary tract infection (UTI), pneumonia, postoperative oxygen supplementation, cardiac arrhythmia, renal disease, sepsis, and periprosthetic joint infections within six months of surgery were recorded. Results Of the 155 elective TJA performed in 2021, 24 patients had a prior COVID+ diagnosis with a mean of 253 days from positive result to surgery date. There were no significant differences in baseline demographics, comorbidities, and preoperative lab markers between groups. Surgeries on patients with a prior COVID+ had a significantly higher EBL (260 vs 175cc), but postoperative outcomes of VTE, UTI, pneumonia, oxygen supplementation requirement, nares MRSA+, cardiac disease, and infection rates between groups were similar. Bivariate logistic regression revealed increased days from COVID+ diagnosis (>6 months) to surgery date were associated with a shorter LOS. Conclusion Although a prior COVID+ diagnosis had increased intraoperative blood loss, there were no significant differences in respiratory, infectious, cardiac, and thromboembolic complications up to six months after elective TJA. This study suggests that asymptomatic C+ patients receiving elective TJA do not require more aggressive prophylactic anticoagulation or antibiotic regimens to prevent VTE or perioperative infections. As institutions around the nation resume pre-COVID rates of arthroplasty surgeries, a prior diagnosis of COVID appears to have no effects on postoperative complications. Cureus 2022-08-13 /pmc/articles/PMC9467498/ /pubmed/36120273 http://dx.doi.org/10.7759/cureus.27974 Text en Copyright © 2022, Lung et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Orthopedics
Lung, Brandon E
Taka, Taha M
Donnelly, Megan
McLellan, Maddison
Callan, Kylie
Issagholian, Leo
Lai, Wilson
So, David
McMaster, William
Yang, Steven
Prior Diagnosis of COVID Has No Increased Complications in Total Joint Arthroplasty
title Prior Diagnosis of COVID Has No Increased Complications in Total Joint Arthroplasty
title_full Prior Diagnosis of COVID Has No Increased Complications in Total Joint Arthroplasty
title_fullStr Prior Diagnosis of COVID Has No Increased Complications in Total Joint Arthroplasty
title_full_unstemmed Prior Diagnosis of COVID Has No Increased Complications in Total Joint Arthroplasty
title_short Prior Diagnosis of COVID Has No Increased Complications in Total Joint Arthroplasty
title_sort prior diagnosis of covid has no increased complications in total joint arthroplasty
topic Orthopedics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467498/
https://www.ncbi.nlm.nih.gov/pubmed/36120273
http://dx.doi.org/10.7759/cureus.27974
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