Design of an optimal combination therapy with broadly neutralizing antibodies to suppress HIV-1

Infusion of broadly neutralizing antibodies (bNAbs) has shown promise as an alternative to anti-retroviral therapy against HIV. A key challenge is to suppress viral escape, which is more effectively achieved with a combination of bNAbs. Here, we propose a computational approach to predict the effica...

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Detalles Bibliográficos
Autores principales: LaMont, Colin, Otwinowski, Jakub, Vanshylla, Kanika, Gruell, Henning, Klein, Florian, Nourmohammad, Armita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467514/
https://www.ncbi.nlm.nih.gov/pubmed/35852143
http://dx.doi.org/10.7554/eLife.76004

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