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Deoxycholic acid induces gastric intestinal metaplasia by activating STAT3 signaling and disturbing gastric bile acids metabolism and microbiota

Intestinal metaplasia (IM) is the inevitable precancerous stage to develop intestinal-type gastric cancer (GC). Deoxycholic acid (DCA) is the main bile acid (BA) component of duodenogastric reflux and has shown an increased concentration during the transition from chronic gastritis to IM associated...

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Detalles Bibliográficos
Autores principales:	Jin, Duochen, Huang, Keting, Xu, Miao, Hua, Hongjin, Ye, Feng, Yan, Jin, Zhang, Guoxin, Wang, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467587/ https://www.ncbi.nlm.nih.gov/pubmed/36067404 http://dx.doi.org/10.1080/19490976.2022.2120744

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