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Novel hydroxyl carboximates derived from β-elemene: design, synthesis and anti-tumour activities evaluation

A series of novel N-alkyl-N-hydroxyl carboximates derived from β-elemene were fortuitously discovered. Most of them showed more potent anti-proliferative activities than their lead compound β-elemene (1). Notably, compound 11i exhibited significant inhibitory effects on the proliferation of three lu...

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Detalles Bibliográficos
Autores principales: Gao, Yuan, Mao, Nian-Dong, Che, Hao, Xu, Li, Bai, Renren, Wang, Li-Wei, Ye, Xiang-Yang, Xie, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467605/
https://www.ncbi.nlm.nih.gov/pubmed/36065895
http://dx.doi.org/10.1080/14756366.2022.2117314