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Novel hydroxyl carboximates derived from β-elemene: design, synthesis and anti-tumour activities evaluation
A series of novel N-alkyl-N-hydroxyl carboximates derived from β-elemene were fortuitously discovered. Most of them showed more potent anti-proliferative activities than their lead compound β-elemene (1). Notably, compound 11i exhibited significant inhibitory effects on the proliferation of three lu...
Autores principales: | Gao, Yuan, Mao, Nian-Dong, Che, Hao, Xu, Li, Bai, Renren, Wang, Li-Wei, Ye, Xiang-Yang, Xie, Tian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467605/ https://www.ncbi.nlm.nih.gov/pubmed/36065895 http://dx.doi.org/10.1080/14756366.2022.2117314 |
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