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Motor neuron-derived induced pluripotent stem cells as a drug screening platform for amyotrophic lateral sclerosis

The development of cell culture models that recapitulate the etiology and features of nervous system diseases is central to the discovery of new drugs and their translation onto therapies. Neuronal tissues are inaccessible due to skeletal constraints and the invasiveness of the procedure to obtain t...

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Detalles Bibliográficos
Autores principales: Amorós, Mariana A., Choi, Esther S., Cofré, Axel R., Dokholyan, Nikolay V., Duzzioni, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467621/
https://www.ncbi.nlm.nih.gov/pubmed/36105357
http://dx.doi.org/10.3389/fcell.2022.962881