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Motor neuron-derived induced pluripotent stem cells as a drug screening platform for amyotrophic lateral sclerosis
The development of cell culture models that recapitulate the etiology and features of nervous system diseases is central to the discovery of new drugs and their translation onto therapies. Neuronal tissues are inaccessible due to skeletal constraints and the invasiveness of the procedure to obtain t...
Autores principales: | Amorós, Mariana A., Choi, Esther S., Cofré, Axel R., Dokholyan, Nikolay V., Duzzioni, Marcelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467621/ https://www.ncbi.nlm.nih.gov/pubmed/36105357 http://dx.doi.org/10.3389/fcell.2022.962881 |
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