Narsoplimab, a Mannan-Binding Lectin-Associated Serine Protease-2 Inhibitor, for the Treatment of Adult Hematopoietic Stem-Cell Transplantation–Associated Thrombotic Microangiopathy

Hematopoietic stem-cell transplantation–associated thrombotic microangiopathy (HSCT-TMA) is a serious complication with significant mortality and no approved therapy. HSCT-TMA results from endothelial injury, which activates the lectin pathway of complement. Narsoplimab (OMS721), an inhibitor of man...

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Detalles Bibliográficos
Autores principales: Khaled, Samer K., Claes, Kathleen, Goh, Yeow Tee, Kwong, Yok Lam, Leung, Nelson, Mendrek, Włodzimierz, Nakamura, Ryotaro, Sathar, Jameela, Ng, Edmund, Nangia, Narinder, Whitaker, Steve, Rambaldi, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467678/
https://www.ncbi.nlm.nih.gov/pubmed/35439028
http://dx.doi.org/10.1200/JCO.21.02389

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