Leukemia Inhibitory Factor Facilitates Self-Renewal and Differentiation and Attenuates Oxidative Stress of BMSCs by Activating PI3K/AKT Signaling

OBJECTIVE: Transplantation of bone marrow-derived mesenchymal stem cells (BMSCs) remains a hopeful therapeutic approach for bone defect reconstruction. Herein, we investigated the effects and mechanisms of leukemia inhibitory factor (LIF) in the function and viability of hypoxic BMSCs as well as bon...

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Detalles Bibliográficos
Autores principales: Liang, Youde, Zhou, Ruiping, Liu, Xin, You, Lin, Chen, Chang, Ye, Xiaoling, Wei, Wei, Liu, Jie, Dai, Jiawei, Li, Kaixiong, Zhao, Xiangxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467750/
https://www.ncbi.nlm.nih.gov/pubmed/36105481
http://dx.doi.org/10.1155/2022/5772509

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