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Hypoxia-inducible factors, mTOR, and astrin constitute an integrative regulatory network in colon cancer cells

Astrin/SPAG5 is a mitotic spindle protein found to be overexpressed in several human cancers, functioning as an oncogene. The expression of Astrin has not been reported so far in colon cancer, nor has it been related to HIFs expression or action. Since mTOR, Astrin, and hypoxia-inducible factors (HI...

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Detalles Bibliográficos
Autores principales:	Saint-Martin, Abril, Morquecho-León, Marco Antonio, Castañeda-Patlán, Maria Cristina, Robles-Flores, Martha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467878/ https://www.ncbi.nlm.nih.gov/pubmed/36111249 http://dx.doi.org/10.1016/j.bbrep.2022.101336

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