A novel anti-B7-H3 chimeric antigen receptor from a single-chain antibody library for immunotherapy of solid cancers

B7-H3 (CD276) has emerged as a target for cancer immunotherapy by virtue of consistent expression in many malignancies, relative absence from healthy tissues, and an emerging role as a driver of tumor immune inhibition. Recent studies have reported B7-H3 to be a suitable target for chimeric antigen...

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Detalles Bibliográficos
Autores principales: Birley, Kathleen, Leboreiro-Babe, Clara, Rota, Enrique Miranda, Buschhaus, Magdalena, Gavriil, Artemis, Vitali, Alice, Alonso-Ferrero, Maria, Hopwood, Lee, Parienti, Lara, Ferry, Gabrielle, Flutter, Barry, Himoudi, Nourredine, Chester, Kerry, Anderson, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467911/
https://www.ncbi.nlm.nih.gov/pubmed/36159778
http://dx.doi.org/10.1016/j.omto.2022.08.008

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