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A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging

cAMP is a key second messenger that regulates diverse cellular functions including neural plasticity. However, the spatiotemporal dynamics of intracellular cAMP in intact organisms are largely unknown due to low sensitivity and/or brightness of current genetically encoded fluorescent cAMP indicators...

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Detalles Bibliográficos
Autores principales: Wang, Liang, Wu, Chunling, Peng, Wanling, Zhou, Ziliang, Zeng, Jianzhi, Li, Xuelin, Yang, Yini, Yu, Shuguang, Zou, Ye, Huang, Mian, Liu, Chang, Chen, Yefei, Li, Yi, Ti, Panpan, Liu, Wenfeng, Gao, Yufeng, Zheng, Wei, Zhong, Haining, Gao, Shangbang, Lu, Zhonghua, Ren, Pei-Gen, Ng, Ho Leung, He, Jie, Chen, Shoudeng, Xu, Min, Li, Yulong, Chu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468011/
https://www.ncbi.nlm.nih.gov/pubmed/36097007
http://dx.doi.org/10.1038/s41467-022-32994-7