Novel lectin-based chimeric antigen receptors target Gb3-positive tumour cells

The link between cancer and aberrant glycosylation has recently become evident. Glycans and their altered forms, known as tumour-associated carbohydrate antigens (TACAs), are diverse, complex and difficult to target therapeutically. Lectins are naturally occurring glycan-binding proteins  that offer...

Descripción completa

Detalles Bibliográficos
Autores principales: Meléndez, Ana Valeria, Velasco Cárdenas, Rubí M.-H., Lagies, Simon, Strietz, Juliane, Siukstaite, Lina, Thomas, Oliver S., Tomisch, Jana, Weber, Wilfried, Kammerer, Bernd, Römer, Winfried, Minguet, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468074/
https://www.ncbi.nlm.nih.gov/pubmed/36097202
http://dx.doi.org/10.1007/s00018-022-04524-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468074/
https://www.ncbi.nlm.nih.gov/pubmed/36097202
http://dx.doi.org/10.1007/s00018-022-04524-7

Ejemplares similares