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Basal ganglia engagement during REM sleep movements in Parkinson’s disease
To elucidate the role of the basal ganglia during REM sleep movements in Parkinson’s disease (PD) we recorded pallidal neural activity from four PD patients. Unlike desynchronization commonly observed during wakeful movements, beta oscillations (13–35 Hz) synchronized during REM sleep movements; fur...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468156/ https://www.ncbi.nlm.nih.gov/pubmed/36097027 http://dx.doi.org/10.1038/s41531-022-00382-z |
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| author | Verma, Ajay K. Acosta Lenis, Sergio Francisco Aman, Joshua E. Sanabria, David Escobar Wang, Jing Pearson, Amy Hill, Meghan Patriat, Remi Schrock, Lauren E. Cooper, Scott E. Park, Michael C. Harel, Noam Howell, Michael J. MacKinnon, Colum D. Vitek, Jerrold L. Johnson, Luke A. |
| author_facet | Verma, Ajay K. Acosta Lenis, Sergio Francisco Aman, Joshua E. Sanabria, David Escobar Wang, Jing Pearson, Amy Hill, Meghan Patriat, Remi Schrock, Lauren E. Cooper, Scott E. Park, Michael C. Harel, Noam Howell, Michael J. MacKinnon, Colum D. Vitek, Jerrold L. Johnson, Luke A. |
| author_sort | Verma, Ajay K. |
| collection | PubMed |
| description | To elucidate the role of the basal ganglia during REM sleep movements in Parkinson’s disease (PD) we recorded pallidal neural activity from four PD patients. Unlike desynchronization commonly observed during wakeful movements, beta oscillations (13–35 Hz) synchronized during REM sleep movements; furthermore, high-frequency oscillations (150–350 Hz) synchronized during movement irrespective of sleep-wake states. Our results demonstrate differential engagement of the basal ganglia during REM sleep and awake movements. |
| format | Online Article Text |
| id | pubmed-9468156 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | Nature Publishing Group UK |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-94681562022-09-14 Basal ganglia engagement during REM sleep movements in Parkinson’s disease Verma, Ajay K. Acosta Lenis, Sergio Francisco Aman, Joshua E. Sanabria, David Escobar Wang, Jing Pearson, Amy Hill, Meghan Patriat, Remi Schrock, Lauren E. Cooper, Scott E. Park, Michael C. Harel, Noam Howell, Michael J. MacKinnon, Colum D. Vitek, Jerrold L. Johnson, Luke A. NPJ Parkinsons Dis Brief Communication To elucidate the role of the basal ganglia during REM sleep movements in Parkinson’s disease (PD) we recorded pallidal neural activity from four PD patients. Unlike desynchronization commonly observed during wakeful movements, beta oscillations (13–35 Hz) synchronized during REM sleep movements; furthermore, high-frequency oscillations (150–350 Hz) synchronized during movement irrespective of sleep-wake states. Our results demonstrate differential engagement of the basal ganglia during REM sleep and awake movements. Nature Publishing Group UK 2022-09-12 /pmc/articles/PMC9468156/ /pubmed/36097027 http://dx.doi.org/10.1038/s41531-022-00382-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
| spellingShingle | Brief Communication Verma, Ajay K. Acosta Lenis, Sergio Francisco Aman, Joshua E. Sanabria, David Escobar Wang, Jing Pearson, Amy Hill, Meghan Patriat, Remi Schrock, Lauren E. Cooper, Scott E. Park, Michael C. Harel, Noam Howell, Michael J. MacKinnon, Colum D. Vitek, Jerrold L. Johnson, Luke A. Basal ganglia engagement during REM sleep movements in Parkinson’s disease |
| title | Basal ganglia engagement during REM sleep movements in Parkinson’s disease |
| title_full | Basal ganglia engagement during REM sleep movements in Parkinson’s disease |
| title_fullStr | Basal ganglia engagement during REM sleep movements in Parkinson’s disease |
| title_full_unstemmed | Basal ganglia engagement during REM sleep movements in Parkinson’s disease |
| title_short | Basal ganglia engagement during REM sleep movements in Parkinson’s disease |
| title_sort | basal ganglia engagement during rem sleep movements in parkinson’s disease |
| topic | Brief Communication |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468156/ https://www.ncbi.nlm.nih.gov/pubmed/36097027 http://dx.doi.org/10.1038/s41531-022-00382-z |
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