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Aire and Fezf2, two regulators in medullary thymic epithelial cells, control autoimmune diseases by regulating TSAs: Partner or complementer?

The expression of tissue-specific antigens (TSAs) in medullary thymic epithelial cells (mTECs) is believed to be responsible for the elimination of autoreactive T cells, a critical process in the maintenance of central immune tolerance. The transcription factor autoimmune regulator (Aire) and FEZ fa...

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Detalles Bibliográficos
Autores principales:	Qi, Yanfei, Zhang, Rongchao, Lu, Yaoping, Zou, Xueyang, Yang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468217/ https://www.ncbi.nlm.nih.gov/pubmed/36110862 http://dx.doi.org/10.3389/fimmu.2022.948259

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