Alzheimer’s Disease Polygenic Risk Score Is Not Associated With Cognitive Decline Among Older Adults With Type 2 Diabetes

OBJECTIVES: Multiple risk loci for late-onset Alzheimer’s disease (LOAD) have been identified. Type 2 diabetes (T2D) is a risk factor for cognitive decline, dementia and Alzheimer’s disease (AD). We investigated the association of polygenic risk score (PRS) for LOAD with overall cognitive functionin...

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Detalles Bibliográficos
Autores principales: Manzali, Sigalit B., Yu, Eric, Ravona-Springer, Ramit, Livny, Abigail, Golan, Sapir, Ouyang, Yuxia, Lesman-Segev, Orit, Liu, Lang, Ganmore, Ithamar, Alkelai, Anna, Gan-Or, Ziv, Lin, Hung-Mo, Heymann, Anthony, Schnaider Beeri, Michal, Greenbaum, Lior
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468264/
https://www.ncbi.nlm.nih.gov/pubmed/36110429
http://dx.doi.org/10.3389/fnagi.2022.853695

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