Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease

Age-related changes to the genome-wide DNA methylation (DNAm) pattern observed in blood are well-documented. Clonal hematopoiesis of indeterminate potential (CHIP), characterized by the age-related acquisition and expansion of leukemogenic mutations in hematopoietic stem cells (HSCs), is associated...

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Detalles Bibliográficos
Autores principales: Uddin, M d Mesbah, Nguyen, Ngoc Quynh H., Yu, Bing, Brody, Jennifer A., Pampana, Akhil, Nakao, Tetsushi, Fornage, Myriam, Bressler, Jan, Sotoodehnia, Nona, Weinstock, Joshua S., Honigberg, Michael C., Nachun, Daniel, Bhattacharya, Romit, Griffin, Gabriel K., Chander, Varuna, Gibbs, Richard A., Rotter, Jerome I., Liu, Chunyu, Baccarelli, Andrea A., Chasman, Daniel I., Whitsel, Eric A., Kiel, Douglas P., Murabito, Joanne M., Boerwinkle, Eric, Ebert, Benjamin L., Jaiswal, Siddhartha, Floyd, James S., Bick, Alexander G., Ballantyne, Christie M., Psaty, Bruce M., Natarajan, Pradeep, Conneely, Karen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468335/
https://www.ncbi.nlm.nih.gov/pubmed/36097025
http://dx.doi.org/10.1038/s41467-022-33093-3

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