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MCM7 supports the stemness of bladder cancer stem-like cells by enhancing autophagic flux

Autophagy plays critical roles in the pluripotent stemness of cancer stem cells (CSCs). However, how CSCs maintain the elevated autophagy to support stemness remains elusive. Here, we demonstrate that bladder cancer stem-like cells (BCSLCs) are at slow-cycling state with enhanced autophagy and mitop...

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Detalles Bibliográficos
Autores principales: Mo, Lijun, Su, Bijia, Xu, Lili, Hu, Zhiming, Li, Hongwei, Du, Hongyan, Li, Jinlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468384/
https://www.ncbi.nlm.nih.gov/pubmed/36111256
http://dx.doi.org/10.1016/j.isci.2022.105029

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