Cargando…

Capsaicin ameliorates diabetic retinopathy by inhibiting poldip2-induced oxidative stress

BACKGROUND: Oxidative stress and the resultant hyperpermeability play a vital role in the pathogenesis of diabetic retinopathy (DR). Poldip2 has been implicated in H(2)O(2) production, but the effects of capsaicin on poldip2 have not been reported. METHODS: Diabetic Sprague-Dawley (SD) rats induced...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Kou, Gao, Xiang, Hu, Chengyang, Gui, Yanchao, Gui, Siyu, Ni, Qinyu, Tao, Liming, Jiang, Zhengxuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468458/ https://www.ncbi.nlm.nih.gov/pubmed/36088760 http://dx.doi.org/10.1016/j.redox.2022.102460

Ejemplares similares

POLDIP3: At the Crossroad of RNA and DNA Metabolism
por: Singh, Manrose, et al.
Publicado: (2022)

Poldip2/Nox4 Mediates Lipopolysaccharide-Induced Oxidative Stress and Inflammation in Human Lung Epithelial Cells
por: Wang, Yueguo, et al.
Publicado: (2022)

Poldip2 takes a central role in metabolic reprograming
por: Paredes, Felipe, et al.
Publicado: (2018)

Characterization of Poldip2 knockout mice: Avoiding incorrect gene targeting
por: Lassègue, Bernard, et al.
Publicado: (2021)

Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution
por: Björkman, Andrea, et al.
Publicado: (2020)

Poldip2 Knockdown Inhibits Vascular Smooth Muscle Proliferation and Neointima Formation by Regulating the Expression of PCNA and p21
por: Datla, Srinivasa Raju, et al.
Publicado: (2018)

Human Polymerase δ-Interacting Protein 2 (PolDIP2) Inhibits the Formation of Human Tau Oligomers and Fibrils
por: Kasho, Kazutoshi, et al.
Publicado: (2021)

Capsaicin-enriched diet ameliorates autoimmune neuritis in rats
por: Motte, Jeremias, et al.
Publicado: (2018)

Alteration of POLDIP3 Splicing Associated with Loss of Function of TDP-43 in Tissues Affected with ALS
por: Shiga, Atsushi, et al.
Publicado: (2012)

PolDIP2 interacts with human PrimPol and enhances its DNA polymerase activities
por: Guilliam, Thomas A., et al.
Publicado: (2016)

Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy
por: Kikuchi, Daniel S., et al.
Publicado: (2019)

MicroRNA 148a Suppresses Tuberculous Fibrosis by Targeting NOX4 and POLDIP2
por: Woo, Seong Ji, et al.
Publicado: (2022)

ZEB1 regulates bone metabolism in osteoporotic rats through inducing POLDIP2 transcription
por: Zhu, Xianwei, et al.
Publicado: (2022)

Broad antagonism of coronaviruses nsp5 to evade the host antiviral responses by cleaving POLDIP3
por: Wu, Yang, et al.
Publicado: (2023)

Capsaicin prevents degeneration of dopamine neurons by inhibiting glial activation and oxidative stress in the MPTP model of Parkinson's disease
por: Chung, Young C, et al.
Publicado: (2017)

Inhibition of LINE-1 Retrotransposition by Capsaicin
por: Nishikawa, Yuki, et al.
Publicado: (2018)

The Preparation of Capsaicin-Chitosan Microspheres (CCMS) Enteric Coated Tablets
por: Chen, Jian, et al.
Publicado: (2013)

Poldip2 Knockout Results in Perinatal Lethality, Reduced Cellular Growth and Increased Autophagy of Mouse Embryonic Fibroblasts
por: Brown, David I., et al.
Publicado: (2014)

A unique arginine cluster in PolDIP2 enhances nucleotide binding and DNA synthesis by PrimPol
por: Kasho, Kazutoshi, et al.
Publicado: (2021)

Crystal structure and molecular dynamics of human POLDIP2, a multifaceted adaptor protein in metabolism and genome stability
por: Kulik, Anastasija A., et al.
Publicado: (2021)

Knockout of AMD-associated gene POLDIP2 reduces mitochondrial superoxide in human retinal pigment epithelial cells
por: Nguyen, Tu, et al.
Publicado: (2023)

Capsaicin Ameliorates the Cyclophosphamide-Induced Cardiotoxicity by Inhibiting Free Radicals Generation, Inflammatory Cytokines, and Apoptotic Pathway in Rats
por: Ahmed, Rayan A., et al.
Publicado: (2023)

Naja naja atra venom ameliorates pulmonary fibrosis by inhibiting inflammatory response and oxidative stress
por: Cui, Kui, et al.
Publicado: (2014)

Poldip2 controls leukocyte infiltration into the ischemic brain by regulating focal adhesion kinase-mediated VCAM-1 induction
por: Eidson, Lori N., et al.
Publicado: (2021)

Oxidative Stress and Diabetic Retinopathy
por: Kowluru, Renu A., et al.
Publicado: (2007)

Oxidative Stress in Diabetic Retinopathy
por: Ortega, Ángel L.
Publicado: (2021)

Capsaicin for Rhinitis
por: Fokkens, Wytske, et al.
Publicado: (2016)

Capsaicin Ameliorates Cisplatin-Induced Renal Injury through Induction of Heme Oxygenase-1
por: Jung, Sung-Hyun, et al.
Publicado: (2014)

Improvement of wound healing by capsaicin through suppression of the inflammatory response and amelioration of the repair process
por: Huang, Chi-Jung, et al.
Publicado: (2023)

Relationship between the Antifungal Activity of Chitosan–Capsaicin Nanoparticles and the Oxidative Stress Response on Aspergillus parasiticus
por: Hernández-Téllez, Cynthia Nazareth, et al.
Publicado: (2022)

Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer
por: Paredes, Felipe, et al.
Publicado: (2018)

Coumestrol mitigates retinal cell inflammation, apoptosis, and oxidative stress in a rat model of diabetic retinopathy via activation of SIRT1
por: Xu, Yanchao, et al.
Publicado: (2021)

Lycium barbarum Polysaccharides and Capsaicin Inhibit Oxidative Stress, Inflammatory Responses, and Pain Signaling in Rats with Dextran Sulfate Sodium-Induced Colitis
por: Chen, Yu-Shan, et al.
Publicado: (2022)

Hyperoside Ameliorates Diabetic Retinopathy via Anti-Oxidation, Inhibiting Cell Damage and Apoptosis Induced by High Glucose
por: Wu, Wei, et al.
Publicado: (2020)

Ischemic Retinopathies: Oxidative Stress and Inflammation
por: Rivera, José Carlos, et al.
Publicado: (2017)

Oxidative Stress Markers and the Retinopathy of Prematurity
por: Graziosi, Alessandro, et al.
Publicado: (2020)

Eicosanoids and Oxidative Stress in Diabetic Retinopathy
por: Wang, Mong-Heng, et al.
Publicado: (2020)

Myeloid Poldip2 Contributes to the Development of Pulmonary Inflammation by Regulating Neutrophil Adhesion in a Murine Model of Acute Respiratory Distress Syndrome
por: Ou, Ziwei, et al.
Publicado: (2022)

Oral supplementation with capsaicin reduces oxidative stress and IL-33 on a food allergy murine model
por: Antunes, Maísa Mota, et al.
Publicado: (2019)

Zonisamide Ameliorates Cognitive Impairment by Inhibiting ER Stress in a Mouse Model of Type 2 Diabetes Mellitus
por: He, Yong-Xiang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_r3uq1ngj902fcgv9nd8js5rsq9