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Exploring the deactivation mechanism of human β (2) adrenergic receptor by accelerated molecular dynamic simulations

The β (2) adrenergic receptor (β(2)AR), one of important members of the G protein coupled receptors (GPCRs), has been suggested as an important target for cardiac and asthma drugs. Two replicas of Gaussian accelerated molecular dynamics (GaMD) simulations are performed to explore the deactivation me...

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Detalles Bibliográficos
Autores principales:	Chen, Jianzhong, Wang, Jian, Zeng, Qingkai, Wang, Wei, Sun, Haibo, Wei, Benzheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468641/ https://www.ncbi.nlm.nih.gov/pubmed/36111136 http://dx.doi.org/10.3389/fmolb.2022.972463

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