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A case of congenital cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects syndrome and a successful pregnancy

Herein, we report an exceptionally rare case of a 25-year-old woman with cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects (OEIS) syndrome achieving a viable pregnancy despite many gastrointestinal and genitourinary malformations and multiple respective corrective operations. T...

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Detalles Bibliográficos
Autores principales: Seat, Mara, Boxwalla, Munira, Hough, Arielle, Goodwin, Glenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Reproductive Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468692/
https://www.ncbi.nlm.nih.gov/pubmed/36097738
http://dx.doi.org/10.5653/cerm.2021.05148
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author Seat, Mara
Boxwalla, Munira
Hough, Arielle
Goodwin, Glenn
author_facet Seat, Mara
Boxwalla, Munira
Hough, Arielle
Goodwin, Glenn
author_sort Seat, Mara
collection PubMed
description Herein, we report an exceptionally rare case of a 25-year-old woman with cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects (OEIS) syndrome achieving a viable pregnancy despite many gastrointestinal and genitourinary malformations and multiple respective corrective operations. The patient was born with two vaginas, two uteruses, four ovaries, an imperforate anus, a large omphalocele including bowel and bladder exstrophy, and diaphysis of the pubic rami. This patient is the only documented OEIS patient not to have tethered spinal cord as an anomaly, perhaps contributing to her successful pregnancy. After experiencing preeclampsia with severe features at 35 weeks, the baby was born via cesarean section.
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spelling pubmed-94686922022-09-16 A case of congenital cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects syndrome and a successful pregnancy Seat, Mara Boxwalla, Munira Hough, Arielle Goodwin, Glenn Clin Exp Reprod Med Case Report Herein, we report an exceptionally rare case of a 25-year-old woman with cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects (OEIS) syndrome achieving a viable pregnancy despite many gastrointestinal and genitourinary malformations and multiple respective corrective operations. The patient was born with two vaginas, two uteruses, four ovaries, an imperforate anus, a large omphalocele including bowel and bladder exstrophy, and diaphysis of the pubic rami. This patient is the only documented OEIS patient not to have tethered spinal cord as an anomaly, perhaps contributing to her successful pregnancy. After experiencing preeclampsia with severe features at 35 weeks, the baby was born via cesarean section. Korean Society for Reproductive Medicine 2022-09 2022-09-01 /pmc/articles/PMC9468692/ /pubmed/36097738 http://dx.doi.org/10.5653/cerm.2021.05148 Text en Copyright © 2022. THE KOREAN SOCIETY FOR REPRODUCTIVE MEDICINE https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Seat, Mara
Boxwalla, Munira
Hough, Arielle
Goodwin, Glenn
A case of congenital cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects syndrome and a successful pregnancy
title A case of congenital cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects syndrome and a successful pregnancy
title_full A case of congenital cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects syndrome and a successful pregnancy
title_fullStr A case of congenital cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects syndrome and a successful pregnancy
title_full_unstemmed A case of congenital cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects syndrome and a successful pregnancy
title_short A case of congenital cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects syndrome and a successful pregnancy
title_sort case of congenital cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects syndrome and a successful pregnancy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468692/
https://www.ncbi.nlm.nih.gov/pubmed/36097738
http://dx.doi.org/10.5653/cerm.2021.05148
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