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Impact of local anesthetics on epigenetics in cancer
Defective silencing of tumor suppressor genes through epigenetic alterations contributes to oncogenesis by perturbing cell cycle regulation, DNA repair or cell death mechanisms. Reversal of such epigenetic changes including DNA hypermethylation provides a promising anticancer strategy. Until now, th...
Autores principales: | Bezu, Lucillia, Kepp, Oliver, Kroemer, Guido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468863/ https://www.ncbi.nlm.nih.gov/pubmed/36110954 http://dx.doi.org/10.3389/fonc.2022.849895 |
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