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Loss of Fas Receptor Function Preserves Photoreceptor Structure and Function in Two Mouse Models of Inherited Retinal Degeneration

PURPOSE: The genetic heterogeneity of inherited retinal degeneration (IRD) has limited the development of mutation-specific therapies, necessitating the development of therapeutic approaches targeting broadly shared pathophysiologic pathways. The Fas receptor has been reported as a contributor to re...

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Detalles Bibliográficos
Autores principales: Yao, Jingyu, Wang, Tiantian, Jia, Lin, Qiu, Yaoyan, Zacks, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469031/
https://www.ncbi.nlm.nih.gov/pubmed/36083588
http://dx.doi.org/10.1167/iovs.63.10.5