Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase

[Image: see text] There is a pressing need for new medicines to prevent and treat malaria. Most antimalarial drug discovery is reliant upon phenotypic screening. However, with the development of improved target validation strategies, target-focused approaches are now being utilized. Here, we describ...

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Detalles Bibliográficos
Autores principales: Milne, Rachel, Wiedemar, Natalie, Corpas-Lopez, Victoriano, Moynihan, Eoin, Wall, Richard J., Dawson, Alice, Robinson, David A., Shepherd, Sharon M., Smith, Robert J., Hallyburton, Irene, Post, John M., Dowers, Karen, Torrie, Leah S., Gilbert, Ian H., Baragaña, Beatriz, Patterson, Stephen, Wyllie, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469095/
https://www.ncbi.nlm.nih.gov/pubmed/36037410
http://dx.doi.org/10.1021/acsinfecdis.2c00364

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