Comparative Evaluation of Efficacy of Bioactive Glass, Tricalcium Phosphate, and Ozone Remineralizing Agents on Artificial Carious Lesion

OBJECTIVES: Evaluation of efficacy of bioactive glass (BAG), tricalcium phosphate, and ozone remineralizing agents on artificial carious lesion. MATERIALS AND METHODS: Freshly extracted 48 human premolar teeth were included for this in vitro study. Remineralization of demineralized teeth was done with respective remineralizing agents (Group A – calcium sodium phosphosilicate [BAG], Group B – tricalcium phosphate [Clinpro Tooth Crème], Group C – ozone remineralizing agents, and control group: Group D – deionized water) three times a day for 12 days for 4 min. The degree of demineralization and remineralization was evaluated with Vickers hardness number. RESULTS: There was a decrease in microhardness from baseline to demineralization in all the groups. The difference in microhardness values from demineralization to remineralization in all the three test groups was found to be statistically highly significant. CONCLUSION: BAG and Tricalcium phosphate had higher remineralizing capacity, which can be used clinically to treat early carious lesions.