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Spectrophotometric Analysis of Fluoride Concentration in Dentifrices for Children in India

BACKGROUND: There is a need to monitor the fluoride content of dentifrices used for children in a country like India, where there is prevalence of endemic fluorosis. AIM: To evaluate the fluoride content of dentifrices for children available in India. SETTINGS AND DESIGN: In vitro study in a laborat...

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Autores principales: Pillai, Dinesh Dhamodhar Mathevan, Vijayaraghavan, R., Kumar, Rajeswary, Prasad, Kota Bala Chaithanya, Pandya, Kalpa, Nagappan, Nagappan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469247/
https://www.ncbi.nlm.nih.gov/pubmed/36110806
http://dx.doi.org/10.4103/jpbs.jpbs_847_21
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author Pillai, Dinesh Dhamodhar Mathevan
Vijayaraghavan, R.
Kumar, Rajeswary
Prasad, Kota Bala Chaithanya
Pandya, Kalpa
Nagappan, Nagappan
author_facet Pillai, Dinesh Dhamodhar Mathevan
Vijayaraghavan, R.
Kumar, Rajeswary
Prasad, Kota Bala Chaithanya
Pandya, Kalpa
Nagappan, Nagappan
author_sort Pillai, Dinesh Dhamodhar Mathevan
collection PubMed
description BACKGROUND: There is a need to monitor the fluoride content of dentifrices used for children in a country like India, where there is prevalence of endemic fluorosis. AIM: To evaluate the fluoride content of dentifrices for children available in India. SETTINGS AND DESIGN: In vitro study in a laboratory setting. METHODS: About 27 major supermarkets/departmental stores in Chennai city were approached by the investigator. All dentifrices indicated for children, available in these stores were included in the present study. A total of four different dentifrice brands were procured from these outlets. For each brand of dentifrice, three samples were randomly chosen and used for fluoride analysis. The fluoride content was assessed in triplet by using spectrophotometric analysis, by a single blinded examiner. The test sample was compared to a standard solution, in a calibration curve to determine the fluoride concentration. RESULTS: The mean fluoride content of dentifrices, indicated for children was 449.5 ± 26.1 ppm. CONCLUSIONS: All brands of commercially available dentifrices indicated for children had optimum amount of fluoride.
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spelling pubmed-94692472022-09-14 Spectrophotometric Analysis of Fluoride Concentration in Dentifrices for Children in India Pillai, Dinesh Dhamodhar Mathevan Vijayaraghavan, R. Kumar, Rajeswary Prasad, Kota Bala Chaithanya Pandya, Kalpa Nagappan, Nagappan J Pharm Bioallied Sci Original Article BACKGROUND: There is a need to monitor the fluoride content of dentifrices used for children in a country like India, where there is prevalence of endemic fluorosis. AIM: To evaluate the fluoride content of dentifrices for children available in India. SETTINGS AND DESIGN: In vitro study in a laboratory setting. METHODS: About 27 major supermarkets/departmental stores in Chennai city were approached by the investigator. All dentifrices indicated for children, available in these stores were included in the present study. A total of four different dentifrice brands were procured from these outlets. For each brand of dentifrice, three samples were randomly chosen and used for fluoride analysis. The fluoride content was assessed in triplet by using spectrophotometric analysis, by a single blinded examiner. The test sample was compared to a standard solution, in a calibration curve to determine the fluoride concentration. RESULTS: The mean fluoride content of dentifrices, indicated for children was 449.5 ± 26.1 ppm. CONCLUSIONS: All brands of commercially available dentifrices indicated for children had optimum amount of fluoride. Wolters Kluwer - Medknow 2022-07 2022-07-13 /pmc/articles/PMC9469247/ /pubmed/36110806 http://dx.doi.org/10.4103/jpbs.jpbs_847_21 Text en Copyright: © 2022 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Pillai, Dinesh Dhamodhar Mathevan
Vijayaraghavan, R.
Kumar, Rajeswary
Prasad, Kota Bala Chaithanya
Pandya, Kalpa
Nagappan, Nagappan
Spectrophotometric Analysis of Fluoride Concentration in Dentifrices for Children in India
title Spectrophotometric Analysis of Fluoride Concentration in Dentifrices for Children in India
title_full Spectrophotometric Analysis of Fluoride Concentration in Dentifrices for Children in India
title_fullStr Spectrophotometric Analysis of Fluoride Concentration in Dentifrices for Children in India
title_full_unstemmed Spectrophotometric Analysis of Fluoride Concentration in Dentifrices for Children in India
title_short Spectrophotometric Analysis of Fluoride Concentration in Dentifrices for Children in India
title_sort spectrophotometric analysis of fluoride concentration in dentifrices for children in india
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469247/
https://www.ncbi.nlm.nih.gov/pubmed/36110806
http://dx.doi.org/10.4103/jpbs.jpbs_847_21
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