Assessment of Utility of Lycopene, Selenium, and Vitamin E in Management of Oral Leukoplakia

OBJECTIVES: To assess the utility of lycopene, selenium, and vitamin E in the management of leukoplakia. MATERIALS AND METHODS: In this cross-sectional observational prospective study, 52 patients of oral leukoplakia were divided into 2 groups. Group I patients were prescribed 6 mg of lycopene, 400...

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Detalles Bibliográficos
Autores principales: Manas, Abhigyan, Venkateswararao, CH, Vaid, Shivali, Dhakray Khanna, Vidhi, Muhaseena, M, Alvi, Sadaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469266/
https://www.ncbi.nlm.nih.gov/pubmed/36110830
http://dx.doi.org/10.4103/jpbs.jpbs_63_22
Descripción
Sumario:OBJECTIVES: To assess the utility of lycopene, selenium, and vitamin E in the management of leukoplakia. MATERIALS AND METHODS: In this cross-sectional observational prospective study, 52 patients of oral leukoplakia were divided into 2 groups. Group I patients were prescribed 6 mg of lycopene, 400 I.U. of vitamin E, and 200 μg of selenium twice a day. Group II patients were prescribed a placebo capsule. The clinical improvement was recorded in both groups. RESULTS: The mean pretreatment size of lesion in group I was 9.24 cm(2) and in group II was 8.52 cm(2). Post treatment size was 1.52 cm(2) in group I and 6.28 cm(2) in group II. There was a significant reduction in the size of lesion in group I compared to group II (P < 0.05). CONCLUSION: The treatment with a combination of lycopene, selenium, and vitamin E is useful and effective in managing the cases of oral leukoplakia.

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