Lactate Dehydrogenase: The Beacon of Hope?

Lactate dehydrogenase enzyme (LDH) helps in the conversion of glucose into pyruvic acid during aerobic glycolysis and is found in the cytoplasm of most cells in the human body. When oxidative stress occurs in the body, LDH may be released extracellularly and its level is usually indicative of the se...

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Detalles Bibliográficos
Autores principales: Pandarathodiyil, Anitha Krishnan, Ramanathan, Anand, Garg, Ranjana, Doss, Jennifer Geraldine, Rahman, Fazliny Binti Abd, Ghani, Wan Maria Nabillah, Vijayan, Srinivas Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469326/
https://www.ncbi.nlm.nih.gov/pubmed/36110668
http://dx.doi.org/10.4103/jpbs.jpbs_104_22
Descripción
Sumario:Lactate dehydrogenase enzyme (LDH) helps in the conversion of glucose into pyruvic acid during aerobic glycolysis and is found in the cytoplasm of most cells in the human body. When oxidative stress occurs in the body, LDH may be released extracellularly and its level is usually indicative of the severity of tissue damage. LDH has proved to be an inestimably resourceful marker in early prediction of serious diseases involving extensive tissue or cellular damage. This short communication explores the potential of LDH as a salivary biomarker of cell injury and death.

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