Lactate Dehydrogenase: The Beacon of Hope?

Lactate dehydrogenase enzyme (LDH) helps in the conversion of glucose into pyruvic acid during aerobic glycolysis and is found in the cytoplasm of most cells in the human body. When oxidative stress occurs in the body, LDH may be released extracellularly and its level is usually indicative of the se...

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Autores principales: Pandarathodiyil, Anitha Krishnan, Ramanathan, Anand, Garg, Ranjana, Doss, Jennifer Geraldine, Rahman, Fazliny Binti Abd, Ghani, Wan Maria Nabillah, Vijayan, Srinivas Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469326/
https://www.ncbi.nlm.nih.gov/pubmed/36110668
http://dx.doi.org/10.4103/jpbs.jpbs_104_22
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author Pandarathodiyil, Anitha Krishnan
Ramanathan, Anand
Garg, Ranjana
Doss, Jennifer Geraldine
Rahman, Fazliny Binti Abd
Ghani, Wan Maria Nabillah
Vijayan, Srinivas Prasad
author_facet Pandarathodiyil, Anitha Krishnan
Ramanathan, Anand
Garg, Ranjana
Doss, Jennifer Geraldine
Rahman, Fazliny Binti Abd
Ghani, Wan Maria Nabillah
Vijayan, Srinivas Prasad
author_sort Pandarathodiyil, Anitha Krishnan
collection PubMed
description Lactate dehydrogenase enzyme (LDH) helps in the conversion of glucose into pyruvic acid during aerobic glycolysis and is found in the cytoplasm of most cells in the human body. When oxidative stress occurs in the body, LDH may be released extracellularly and its level is usually indicative of the severity of tissue damage. LDH has proved to be an inestimably resourceful marker in early prediction of serious diseases involving extensive tissue or cellular damage. This short communication explores the potential of LDH as a salivary biomarker of cell injury and death.
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spelling pubmed-94693262022-09-14 Lactate Dehydrogenase: The Beacon of Hope? Pandarathodiyil, Anitha Krishnan Ramanathan, Anand Garg, Ranjana Doss, Jennifer Geraldine Rahman, Fazliny Binti Abd Ghani, Wan Maria Nabillah Vijayan, Srinivas Prasad J Pharm Bioallied Sci Short Communication Lactate dehydrogenase enzyme (LDH) helps in the conversion of glucose into pyruvic acid during aerobic glycolysis and is found in the cytoplasm of most cells in the human body. When oxidative stress occurs in the body, LDH may be released extracellularly and its level is usually indicative of the severity of tissue damage. LDH has proved to be an inestimably resourceful marker in early prediction of serious diseases involving extensive tissue or cellular damage. This short communication explores the potential of LDH as a salivary biomarker of cell injury and death. Wolters Kluwer - Medknow 2022-07 2022-07-13 /pmc/articles/PMC9469326/ /pubmed/36110668 http://dx.doi.org/10.4103/jpbs.jpbs_104_22 Text en Copyright: © 2022 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Short Communication
Pandarathodiyil, Anitha Krishnan
Ramanathan, Anand
Garg, Ranjana
Doss, Jennifer Geraldine
Rahman, Fazliny Binti Abd
Ghani, Wan Maria Nabillah
Vijayan, Srinivas Prasad
Lactate Dehydrogenase: The Beacon of Hope?
title Lactate Dehydrogenase: The Beacon of Hope?
title_full Lactate Dehydrogenase: The Beacon of Hope?
title_fullStr Lactate Dehydrogenase: The Beacon of Hope?
title_full_unstemmed Lactate Dehydrogenase: The Beacon of Hope?
title_short Lactate Dehydrogenase: The Beacon of Hope?
title_sort lactate dehydrogenase: the beacon of hope?
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469326/
https://www.ncbi.nlm.nih.gov/pubmed/36110668
http://dx.doi.org/10.4103/jpbs.jpbs_104_22
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