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Association of Orthodontic Tooth Movement with Leptin Concentration in Gingival Crevicular Fluid

OBJECTIVES: This study aims to evaluate the association of orthodontic tooth movement with the concentration of leptin in gingival crevicular fluid (GCF). MATERIALS AND METHODS: In thirty orthodontic patients, the concentration of leptin was assessed at baseline, 1 h, 24 h, 7 days, and 1 month after...

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Autores principales: Goutam, Manish, Manas, Abhigyan, Kashyap, Arpita, Verghese, Yohan, Jaggi, Namita, Pragna, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469343/
https://www.ncbi.nlm.nih.gov/pubmed/36110689
http://dx.doi.org/10.4103/jpbs.jpbs_805_21
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author Goutam, Manish
Manas, Abhigyan
Kashyap, Arpita
Verghese, Yohan
Jaggi, Namita
Pragna, K
author_facet Goutam, Manish
Manas, Abhigyan
Kashyap, Arpita
Verghese, Yohan
Jaggi, Namita
Pragna, K
author_sort Goutam, Manish
collection PubMed
description OBJECTIVES: This study aims to evaluate the association of orthodontic tooth movement with the concentration of leptin in gingival crevicular fluid (GCF). MATERIALS AND METHODS: In thirty orthodontic patients, the concentration of leptin was assessed at baseline, 1 h, 24 h, 7 days, and 1 month after application of orthodontic force. Distalized tooth movement was evaluated by measuring the difference on dental casts at baseline and 1 month after force application. RESULTS: Average concentration of leptin in GCF raises from baseline (T0) to 1 h after application of force (T1). There was a significant association of the overall average concentration of leptin with the degree of tooth movement (correlation coefficient = 0.625). CONCLUSION: There was a biphasic change in GCF leptin concentration and significant association between rates of tooth movement with GCF leptin concentration.
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spelling pubmed-94693432022-09-14 Association of Orthodontic Tooth Movement with Leptin Concentration in Gingival Crevicular Fluid Goutam, Manish Manas, Abhigyan Kashyap, Arpita Verghese, Yohan Jaggi, Namita Pragna, K J Pharm Bioallied Sci Original Article OBJECTIVES: This study aims to evaluate the association of orthodontic tooth movement with the concentration of leptin in gingival crevicular fluid (GCF). MATERIALS AND METHODS: In thirty orthodontic patients, the concentration of leptin was assessed at baseline, 1 h, 24 h, 7 days, and 1 month after application of orthodontic force. Distalized tooth movement was evaluated by measuring the difference on dental casts at baseline and 1 month after force application. RESULTS: Average concentration of leptin in GCF raises from baseline (T0) to 1 h after application of force (T1). There was a significant association of the overall average concentration of leptin with the degree of tooth movement (correlation coefficient = 0.625). CONCLUSION: There was a biphasic change in GCF leptin concentration and significant association between rates of tooth movement with GCF leptin concentration. Wolters Kluwer - Medknow 2022-07 2022-07-13 /pmc/articles/PMC9469343/ /pubmed/36110689 http://dx.doi.org/10.4103/jpbs.jpbs_805_21 Text en Copyright: © 2022 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Goutam, Manish
Manas, Abhigyan
Kashyap, Arpita
Verghese, Yohan
Jaggi, Namita
Pragna, K
Association of Orthodontic Tooth Movement with Leptin Concentration in Gingival Crevicular Fluid
title Association of Orthodontic Tooth Movement with Leptin Concentration in Gingival Crevicular Fluid
title_full Association of Orthodontic Tooth Movement with Leptin Concentration in Gingival Crevicular Fluid
title_fullStr Association of Orthodontic Tooth Movement with Leptin Concentration in Gingival Crevicular Fluid
title_full_unstemmed Association of Orthodontic Tooth Movement with Leptin Concentration in Gingival Crevicular Fluid
title_short Association of Orthodontic Tooth Movement with Leptin Concentration in Gingival Crevicular Fluid
title_sort association of orthodontic tooth movement with leptin concentration in gingival crevicular fluid
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469343/
https://www.ncbi.nlm.nih.gov/pubmed/36110689
http://dx.doi.org/10.4103/jpbs.jpbs_805_21
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