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Orofacial Features and Their Correlation in Cardiovascular Diseases

BACKGROUND: The association between cardiovascular diseases and periodontitis had different pathophysiological mechanisms involved. These mechanisms are both inflammatory and microbial. Furthermore, the possible association between two diseases can be explained by common risk factors. AIMS: The pres...

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Autores principales: Sinha, Sonal, Toshi, Toshi, Raj, Nikhil, Mankotia, Chahat Singh, Kumari, Khushboo, Irfan, Ahamed KA, Rangari, Priyadarshini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469372/
https://www.ncbi.nlm.nih.gov/pubmed/36110682
http://dx.doi.org/10.4103/jpbs.jpbs_252_21
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author Sinha, Sonal
Toshi, Toshi
Raj, Nikhil
Mankotia, Chahat Singh
Kumari, Khushboo
Irfan, Ahamed KA
Rangari, Priyadarshini
author_facet Sinha, Sonal
Toshi, Toshi
Raj, Nikhil
Mankotia, Chahat Singh
Kumari, Khushboo
Irfan, Ahamed KA
Rangari, Priyadarshini
author_sort Sinha, Sonal
collection PubMed
description BACKGROUND: The association between cardiovascular diseases and periodontitis had different pathophysiological mechanisms involved. These mechanisms are both inflammatory and microbial. Furthermore, the possible association between two diseases can be explained by common risk factors. AIMS: The present trial was carried out to establish a relation between coronary artery disease and periodontitis. MATERIALS AND METHODS: One hundred and twenty-six participants advised for the angiography were included. Periodontists determined the presence of periodontitis in all participants followed by lipid profile, C-reactive protein (CRP) levels, and blood coronary angiography was then performed. The collected data were subjected to the statistical analysis, and the results were formulated. RESULTS: The level of CRP in participants with and without coronary artery disease was 0.66 ± 1.52 and 0.53 ± 1.01, respectively, which was nonsignificant with a P = 0.63. Nonstatistically significant difference was seen in values of cholesterol and blood glucose in participants with and without coronary artery disease (P = 0.28 and P = 0.53). The mean tooth loss in participants with coronary artery disease was 14.2 ± 6.4 and in participants with no coronary artery disease was 11.8 ± 6.5, and such difference was statistically significant (P = 0.05). CONCLUSION: The present study establishes an association between poor oral health, periodontitis, and coronary artery disease. This study demonstrates that tooth loss which is an important feature of periodontitis is significantly associated with coronary artery disease.
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spelling pubmed-94693722022-09-14 Orofacial Features and Their Correlation in Cardiovascular Diseases Sinha, Sonal Toshi, Toshi Raj, Nikhil Mankotia, Chahat Singh Kumari, Khushboo Irfan, Ahamed KA Rangari, Priyadarshini J Pharm Bioallied Sci Original Article BACKGROUND: The association between cardiovascular diseases and periodontitis had different pathophysiological mechanisms involved. These mechanisms are both inflammatory and microbial. Furthermore, the possible association between two diseases can be explained by common risk factors. AIMS: The present trial was carried out to establish a relation between coronary artery disease and periodontitis. MATERIALS AND METHODS: One hundred and twenty-six participants advised for the angiography were included. Periodontists determined the presence of periodontitis in all participants followed by lipid profile, C-reactive protein (CRP) levels, and blood coronary angiography was then performed. The collected data were subjected to the statistical analysis, and the results were formulated. RESULTS: The level of CRP in participants with and without coronary artery disease was 0.66 ± 1.52 and 0.53 ± 1.01, respectively, which was nonsignificant with a P = 0.63. Nonstatistically significant difference was seen in values of cholesterol and blood glucose in participants with and without coronary artery disease (P = 0.28 and P = 0.53). The mean tooth loss in participants with coronary artery disease was 14.2 ± 6.4 and in participants with no coronary artery disease was 11.8 ± 6.5, and such difference was statistically significant (P = 0.05). CONCLUSION: The present study establishes an association between poor oral health, periodontitis, and coronary artery disease. This study demonstrates that tooth loss which is an important feature of periodontitis is significantly associated with coronary artery disease. Wolters Kluwer - Medknow 2022-07 2022-07-13 /pmc/articles/PMC9469372/ /pubmed/36110682 http://dx.doi.org/10.4103/jpbs.jpbs_252_21 Text en Copyright: © 2022 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Sinha, Sonal
Toshi, Toshi
Raj, Nikhil
Mankotia, Chahat Singh
Kumari, Khushboo
Irfan, Ahamed KA
Rangari, Priyadarshini
Orofacial Features and Their Correlation in Cardiovascular Diseases
title Orofacial Features and Their Correlation in Cardiovascular Diseases
title_full Orofacial Features and Their Correlation in Cardiovascular Diseases
title_fullStr Orofacial Features and Their Correlation in Cardiovascular Diseases
title_full_unstemmed Orofacial Features and Their Correlation in Cardiovascular Diseases
title_short Orofacial Features and Their Correlation in Cardiovascular Diseases
title_sort orofacial features and their correlation in cardiovascular diseases
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469372/
https://www.ncbi.nlm.nih.gov/pubmed/36110682
http://dx.doi.org/10.4103/jpbs.jpbs_252_21
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