Cargando…
Comparative Evaluation of Chlorhexidine and Cetrimide as Irrigants in Necrotic Primary Teeth: An In vivo Study
CONTEXT: Disinfection of the root canal system by biomechanical preparation and profuse irrigation is especially important in primary teeth due to its complex pulp canal anatomy. Appropriate selection of irrigating solution should be done in terms of tissue dissolving capacity, antibacterial efficac...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469387/ https://www.ncbi.nlm.nih.gov/pubmed/36110802 http://dx.doi.org/10.4103/jpbs.jpbs_753_21 |
_version_ | 1784788634070679552 |
---|---|
author | Sabu, Nimmy Thomas, Nithya Annie Thimmaiah, Charisma Joseph, Ajay P. Jobe, Justin Palose, Pauline Susan |
author_facet | Sabu, Nimmy Thomas, Nithya Annie Thimmaiah, Charisma Joseph, Ajay P. Jobe, Justin Palose, Pauline Susan |
author_sort | Sabu, Nimmy |
collection | PubMed |
description | CONTEXT: Disinfection of the root canal system by biomechanical preparation and profuse irrigation is especially important in primary teeth due to its complex pulp canal anatomy. Appropriate selection of irrigating solution should be done in terms of tissue dissolving capacity, antibacterial efficacy, and palatability when treating pediatric cases. AIM: The aim of the study was to compare the antibacterial efficacy of 2% chlorhexidine (CHX), 0.2% cetrimide (CTR), and 0.2% CHX + 0.2% CTR against anaerobic bacteria and to test the influence of CTR added to CHX on its antibacterial action. MATERIALS AND METHODS: Seventy-five teeth that were selected for the study were divided into three groups: Group I (2% CHX), Group II (0.2% CTR), and Group III (0. 2% CHX + 0.2% CTR). Samples collected before and after irrigation were immediately processed and microbial growths were quantified. STATISTICAL ANALYSIS: Intergroup comparison was done using one-way analysis of variance and Newman–Keuls multiple post hoc procedures and intragroup comparison was done using paired t-test. RESULTS: When the mean values of Group I were compared with Group II, the data were statistically not significant (P = 0.2341), whereas Group I showed a significant difference when compared with Group III (P = 0.0107). When the mean values of Group II and Group III were compared, the data were found to be statistically not significant (P = 0.0805). CONCLUSION: The efficacy of 2% CHX was found to be slightly superior when compared with that of 0.2% CTR, but the difference was not statistically significant. However, a significant difference was found between 2% CHX and combination irrigants. |
format | Online Article Text |
id | pubmed-9469387 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-94693872022-09-14 Comparative Evaluation of Chlorhexidine and Cetrimide as Irrigants in Necrotic Primary Teeth: An In vivo Study Sabu, Nimmy Thomas, Nithya Annie Thimmaiah, Charisma Joseph, Ajay P. Jobe, Justin Palose, Pauline Susan J Pharm Bioallied Sci Original Article CONTEXT: Disinfection of the root canal system by biomechanical preparation and profuse irrigation is especially important in primary teeth due to its complex pulp canal anatomy. Appropriate selection of irrigating solution should be done in terms of tissue dissolving capacity, antibacterial efficacy, and palatability when treating pediatric cases. AIM: The aim of the study was to compare the antibacterial efficacy of 2% chlorhexidine (CHX), 0.2% cetrimide (CTR), and 0.2% CHX + 0.2% CTR against anaerobic bacteria and to test the influence of CTR added to CHX on its antibacterial action. MATERIALS AND METHODS: Seventy-five teeth that were selected for the study were divided into three groups: Group I (2% CHX), Group II (0.2% CTR), and Group III (0. 2% CHX + 0.2% CTR). Samples collected before and after irrigation were immediately processed and microbial growths were quantified. STATISTICAL ANALYSIS: Intergroup comparison was done using one-way analysis of variance and Newman–Keuls multiple post hoc procedures and intragroup comparison was done using paired t-test. RESULTS: When the mean values of Group I were compared with Group II, the data were statistically not significant (P = 0.2341), whereas Group I showed a significant difference when compared with Group III (P = 0.0107). When the mean values of Group II and Group III were compared, the data were found to be statistically not significant (P = 0.0805). CONCLUSION: The efficacy of 2% CHX was found to be slightly superior when compared with that of 0.2% CTR, but the difference was not statistically significant. However, a significant difference was found between 2% CHX and combination irrigants. Wolters Kluwer - Medknow 2022-07 2022-07-13 /pmc/articles/PMC9469387/ /pubmed/36110802 http://dx.doi.org/10.4103/jpbs.jpbs_753_21 Text en Copyright: © 2022 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Sabu, Nimmy Thomas, Nithya Annie Thimmaiah, Charisma Joseph, Ajay P. Jobe, Justin Palose, Pauline Susan Comparative Evaluation of Chlorhexidine and Cetrimide as Irrigants in Necrotic Primary Teeth: An In vivo Study |
title | Comparative Evaluation of Chlorhexidine and Cetrimide as Irrigants in Necrotic Primary Teeth: An In vivo Study |
title_full | Comparative Evaluation of Chlorhexidine and Cetrimide as Irrigants in Necrotic Primary Teeth: An In vivo Study |
title_fullStr | Comparative Evaluation of Chlorhexidine and Cetrimide as Irrigants in Necrotic Primary Teeth: An In vivo Study |
title_full_unstemmed | Comparative Evaluation of Chlorhexidine and Cetrimide as Irrigants in Necrotic Primary Teeth: An In vivo Study |
title_short | Comparative Evaluation of Chlorhexidine and Cetrimide as Irrigants in Necrotic Primary Teeth: An In vivo Study |
title_sort | comparative evaluation of chlorhexidine and cetrimide as irrigants in necrotic primary teeth: an in vivo study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469387/ https://www.ncbi.nlm.nih.gov/pubmed/36110802 http://dx.doi.org/10.4103/jpbs.jpbs_753_21 |
work_keys_str_mv | AT sabunimmy comparativeevaluationofchlorhexidineandcetrimideasirrigantsinnecroticprimaryteethaninvivostudy AT thomasnithyaannie comparativeevaluationofchlorhexidineandcetrimideasirrigantsinnecroticprimaryteethaninvivostudy AT thimmaiahcharisma comparativeevaluationofchlorhexidineandcetrimideasirrigantsinnecroticprimaryteethaninvivostudy AT josephajayp comparativeevaluationofchlorhexidineandcetrimideasirrigantsinnecroticprimaryteethaninvivostudy AT jobejustin comparativeevaluationofchlorhexidineandcetrimideasirrigantsinnecroticprimaryteethaninvivostudy AT palosepaulinesusan comparativeevaluationofchlorhexidineandcetrimideasirrigantsinnecroticprimaryteethaninvivostudy |