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Antimicrobial Efficacy of Herbal and Chlorhexidine Mouthrinse against Staphylococcus aureus - An in vitro Microbiological Study

BACKGROUND: Microorganisms in the oral cavity are still considered serious public health problems and position a costly burden on health-care services worldwide and elsewhere. Mouthrinses have been used in the oral cavity for decades with the intention of reducing the amount of microorganisms. Mouth...

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Autores principales: Nagappan, Nagappan, Palaneeswaran, Kamalashankar, Kumarappan, Kannan, Natarajan, Raghunathan, Tajuddin, Rameezuddin, Anusha, Yalamanchi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469420/
https://www.ncbi.nlm.nih.gov/pubmed/36110729
http://dx.doi.org/10.4103/jpbs.jpbs_821_21
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author Nagappan, Nagappan
Palaneeswaran, Kamalashankar
Kumarappan, Kannan
Natarajan, Raghunathan
Tajuddin, Rameezuddin
Anusha, Yalamanchi
author_facet Nagappan, Nagappan
Palaneeswaran, Kamalashankar
Kumarappan, Kannan
Natarajan, Raghunathan
Tajuddin, Rameezuddin
Anusha, Yalamanchi
author_sort Nagappan, Nagappan
collection PubMed
description BACKGROUND: Microorganisms in the oral cavity are still considered serious public health problems and position a costly burden on health-care services worldwide and elsewhere. Mouthrinses have been used in the oral cavity for decades with the intention of reducing the amount of microorganisms. Mouthrinses are used as additives to oral mechanical hygiene. Therapeutic mouthwashes are also prescribed as an alternative to mechanical plaque control for plaque accumulation prevention and for gingival and peri-implant health maintenance. Mechanical control alone has been questioned to eliminate recalcitrant biofilms in the oral cavity because it is known to be very time-consuming and, most significantly, inadequate for good oral hygiene. The aim of this study was to assess the minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and antimicrobial efficacy of herbal and chlorhexidine (CHX) mouthrinse against Staphylococcus aureus. MATERIALS AND METHODS: For MIC (macrobroth dilution method), MBC and antimicrobial effectiveness (zone of inhibition) of an herbal mouthrinse and 0.2% CHX mouthrinse were determined by the agar well diffusion method. RESULTS: The zone of inhibition of S. aureus was 24 mm for the CHX mouthrinse. The arowash liquid mouthrinse shows that S. aureus does not produce a zone of inhibition. CONCLUSION: CHX mouthrinse (0.2%) has a better antimicrobial efficacy against the S. mutans when compared to herbal mouthrinse (arowash liquid)
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spelling pubmed-94694202022-09-14 Antimicrobial Efficacy of Herbal and Chlorhexidine Mouthrinse against Staphylococcus aureus - An in vitro Microbiological Study Nagappan, Nagappan Palaneeswaran, Kamalashankar Kumarappan, Kannan Natarajan, Raghunathan Tajuddin, Rameezuddin Anusha, Yalamanchi J Pharm Bioallied Sci Original Article BACKGROUND: Microorganisms in the oral cavity are still considered serious public health problems and position a costly burden on health-care services worldwide and elsewhere. Mouthrinses have been used in the oral cavity for decades with the intention of reducing the amount of microorganisms. Mouthrinses are used as additives to oral mechanical hygiene. Therapeutic mouthwashes are also prescribed as an alternative to mechanical plaque control for plaque accumulation prevention and for gingival and peri-implant health maintenance. Mechanical control alone has been questioned to eliminate recalcitrant biofilms in the oral cavity because it is known to be very time-consuming and, most significantly, inadequate for good oral hygiene. The aim of this study was to assess the minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and antimicrobial efficacy of herbal and chlorhexidine (CHX) mouthrinse against Staphylococcus aureus. MATERIALS AND METHODS: For MIC (macrobroth dilution method), MBC and antimicrobial effectiveness (zone of inhibition) of an herbal mouthrinse and 0.2% CHX mouthrinse were determined by the agar well diffusion method. RESULTS: The zone of inhibition of S. aureus was 24 mm for the CHX mouthrinse. The arowash liquid mouthrinse shows that S. aureus does not produce a zone of inhibition. CONCLUSION: CHX mouthrinse (0.2%) has a better antimicrobial efficacy against the S. mutans when compared to herbal mouthrinse (arowash liquid) Wolters Kluwer - Medknow 2022-07 2022-07-13 /pmc/articles/PMC9469420/ /pubmed/36110729 http://dx.doi.org/10.4103/jpbs.jpbs_821_21 Text en Copyright: © 2022 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Nagappan, Nagappan
Palaneeswaran, Kamalashankar
Kumarappan, Kannan
Natarajan, Raghunathan
Tajuddin, Rameezuddin
Anusha, Yalamanchi
Antimicrobial Efficacy of Herbal and Chlorhexidine Mouthrinse against Staphylococcus aureus - An in vitro Microbiological Study
title Antimicrobial Efficacy of Herbal and Chlorhexidine Mouthrinse against Staphylococcus aureus - An in vitro Microbiological Study
title_full Antimicrobial Efficacy of Herbal and Chlorhexidine Mouthrinse against Staphylococcus aureus - An in vitro Microbiological Study
title_fullStr Antimicrobial Efficacy of Herbal and Chlorhexidine Mouthrinse against Staphylococcus aureus - An in vitro Microbiological Study
title_full_unstemmed Antimicrobial Efficacy of Herbal and Chlorhexidine Mouthrinse against Staphylococcus aureus - An in vitro Microbiological Study
title_short Antimicrobial Efficacy of Herbal and Chlorhexidine Mouthrinse against Staphylococcus aureus - An in vitro Microbiological Study
title_sort antimicrobial efficacy of herbal and chlorhexidine mouthrinse against staphylococcus aureus - an in vitro microbiological study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469420/
https://www.ncbi.nlm.nih.gov/pubmed/36110729
http://dx.doi.org/10.4103/jpbs.jpbs_821_21
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