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Antimicrobial Prescription Patterns among Oral Implantologists of Kerala, India: A Cross-Sectional Survey
BACKGROUND AND OBJECTIVES: Antimicrobial resistance is a grave public health concern, and it is important to optimize the use of antimicrobials in dental surgeries. Antimicrobial prescriptions in dental implant placements are often empiric and not guided by consensus or specific guidelines. The aim...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469451/ https://www.ncbi.nlm.nih.gov/pubmed/36110751 http://dx.doi.org/10.4103/jpbs.jpbs_744_21 |
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author | George, Annie Kitty Narayan, Vivek Joseph, Betsy Balram, Bindya Anil, Sukumaran |
author_facet | George, Annie Kitty Narayan, Vivek Joseph, Betsy Balram, Bindya Anil, Sukumaran |
author_sort | George, Annie Kitty |
collection | PubMed |
description | BACKGROUND AND OBJECTIVES: Antimicrobial resistance is a grave public health concern, and it is important to optimize the use of antimicrobials in dental surgeries. Antimicrobial prescriptions in dental implant placements are often empiric and not guided by consensus or specific guidelines. The aim of this study was to elucidate antibiotic prescribing patterns among oral implantologists. The objectives were to identify the frequency of antimicrobial usage and preferences regarding the perioperative timing of prescriptions, type of antibiotic, dosage, and duration in different implant placement scenarios. SUBJECTS AND METHODS: An anonymized web-based survey was carried out. Participants were drawn from the lists of oral implantologists from all local branches of the Indian Dental Association in the state of Kerala, India, until the required sample size was met. Responses were recorded using an Internet-based validated questionnaire sent via e-mail to the participants. The questionnaire contained five sections with both open-ended and closed-ended questions. RESULTS: Among the 93 participants, 59% of the dental implantologists preferred 0.2% povidone-iodine as a preprocedural mouth rinse in the backdrop of the COVID-19 pandemic, and 68% prescribed 0.12%–0.2% chlorhexidine as the postoperative mouth rinse. The majority of the participants (73%) routinely prescribed systemic antibiotics perioperatively during implant placement surgery. Interestingly, while none of the participants preferred a solely preoperative regimen, 92.4% of the dentists in our survey prescribed both pre- and postoperative antibiotics. Antibiotics of choice as the preoperative agents were amoxicillin and amoxicillin plus clavulanic acid. The most preferred postoperative agent was amoxicillin plus clavulanic acid. The popularly reported rationale behind a preoperative antibiotic was to decrease or eliminate local or systemic infections (79%), and the majority of the participants (60%) prescribed postoperative antibiotics to prevent postoperative infection. CONCLUSIONS: Systemic antibiotic prescriptions in implant placement surgery are not based on currently available evidence. Most oral implantologists who participated in the survey prescribed systemic antibiotics to prevent perioperative infection, even in simple and straightforward implant placements. Specific guidelines need to be generated in complex implant placement situations and implant placement in medically compromised patients to prevent excessive prescriptions. |
format | Online Article Text |
id | pubmed-9469451 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-94694512022-09-14 Antimicrobial Prescription Patterns among Oral Implantologists of Kerala, India: A Cross-Sectional Survey George, Annie Kitty Narayan, Vivek Joseph, Betsy Balram, Bindya Anil, Sukumaran J Pharm Bioallied Sci Original Article BACKGROUND AND OBJECTIVES: Antimicrobial resistance is a grave public health concern, and it is important to optimize the use of antimicrobials in dental surgeries. Antimicrobial prescriptions in dental implant placements are often empiric and not guided by consensus or specific guidelines. The aim of this study was to elucidate antibiotic prescribing patterns among oral implantologists. The objectives were to identify the frequency of antimicrobial usage and preferences regarding the perioperative timing of prescriptions, type of antibiotic, dosage, and duration in different implant placement scenarios. SUBJECTS AND METHODS: An anonymized web-based survey was carried out. Participants were drawn from the lists of oral implantologists from all local branches of the Indian Dental Association in the state of Kerala, India, until the required sample size was met. Responses were recorded using an Internet-based validated questionnaire sent via e-mail to the participants. The questionnaire contained five sections with both open-ended and closed-ended questions. RESULTS: Among the 93 participants, 59% of the dental implantologists preferred 0.2% povidone-iodine as a preprocedural mouth rinse in the backdrop of the COVID-19 pandemic, and 68% prescribed 0.12%–0.2% chlorhexidine as the postoperative mouth rinse. The majority of the participants (73%) routinely prescribed systemic antibiotics perioperatively during implant placement surgery. Interestingly, while none of the participants preferred a solely preoperative regimen, 92.4% of the dentists in our survey prescribed both pre- and postoperative antibiotics. Antibiotics of choice as the preoperative agents were amoxicillin and amoxicillin plus clavulanic acid. The most preferred postoperative agent was amoxicillin plus clavulanic acid. The popularly reported rationale behind a preoperative antibiotic was to decrease or eliminate local or systemic infections (79%), and the majority of the participants (60%) prescribed postoperative antibiotics to prevent postoperative infection. CONCLUSIONS: Systemic antibiotic prescriptions in implant placement surgery are not based on currently available evidence. Most oral implantologists who participated in the survey prescribed systemic antibiotics to prevent perioperative infection, even in simple and straightforward implant placements. Specific guidelines need to be generated in complex implant placement situations and implant placement in medically compromised patients to prevent excessive prescriptions. Wolters Kluwer - Medknow 2022-07 2022-07-13 /pmc/articles/PMC9469451/ /pubmed/36110751 http://dx.doi.org/10.4103/jpbs.jpbs_744_21 Text en Copyright: © 2022 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article George, Annie Kitty Narayan, Vivek Joseph, Betsy Balram, Bindya Anil, Sukumaran Antimicrobial Prescription Patterns among Oral Implantologists of Kerala, India: A Cross-Sectional Survey |
title | Antimicrobial Prescription Patterns among Oral Implantologists of Kerala, India: A Cross-Sectional Survey |
title_full | Antimicrobial Prescription Patterns among Oral Implantologists of Kerala, India: A Cross-Sectional Survey |
title_fullStr | Antimicrobial Prescription Patterns among Oral Implantologists of Kerala, India: A Cross-Sectional Survey |
title_full_unstemmed | Antimicrobial Prescription Patterns among Oral Implantologists of Kerala, India: A Cross-Sectional Survey |
title_short | Antimicrobial Prescription Patterns among Oral Implantologists of Kerala, India: A Cross-Sectional Survey |
title_sort | antimicrobial prescription patterns among oral implantologists of kerala, india: a cross-sectional survey |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469451/ https://www.ncbi.nlm.nih.gov/pubmed/36110751 http://dx.doi.org/10.4103/jpbs.jpbs_744_21 |
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