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Sub-mucosal Dexamethasone for Post-operative Pain and Oedema Control in Lower Third Molar Surgery

BACKGROUND: Surgical excision of the problematic mandibular third molars causes substantial tissue damage and an inflammatory response. Discomfort and edema are common postoperative signs and symptoms caused by the latter. To find out whether dexamethasone may help with the edema and pain that come...

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Autores principales: Virkar, Yogiraj B., Chawla, Jitendra, Changmai, Arindom, Kumar, Krishna, Abhishek, Kumar, Jawaid, Moazzam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469457/
https://www.ncbi.nlm.nih.gov/pubmed/36110784
http://dx.doi.org/10.4103/jpbs.jpbs_8_22
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author Virkar, Yogiraj B.
Chawla, Jitendra
Changmai, Arindom
Kumar, Krishna
Abhishek, Kumar
Jawaid, Moazzam
author_facet Virkar, Yogiraj B.
Chawla, Jitendra
Changmai, Arindom
Kumar, Krishna
Abhishek, Kumar
Jawaid, Moazzam
author_sort Virkar, Yogiraj B.
collection PubMed
description BACKGROUND: Surgical excision of the problematic mandibular third molars causes substantial tissue damage and an inflammatory response. Discomfort and edema are common postoperative signs and symptoms caused by the latter. To find out whether dexamethasone may help with the edema and pain that come along with the surgical removal of impacted mandibular third molars, researchers have performed clinical studies. METHODS: Twenty individuals with bilaterally affected mandibular third molars who were scheduled for extraction participated in a prospective trial. At two separate sessions, teeth were raised and cut after buccal ostectomy. Since the surgical operation on the left foot, both patients were administered a mixture of 4 mg dexamethasone submucosal injection and antibiotics for 3 days. On the 1(st), 3(rd), and 7(th) postoperative days, edema and pain were assessed. RESULTS: At the 1(st), 3(rd), and 7(th) postoperative days, there was a clinically meaningful decrease in the level of edema and discomfort in both arms. CONCLUSIONS: The current report offers empirical proof that administering a 4 mg dexamethasone submucosal injection during surgery greatly reduced post-surgical edema and discomfort.
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spelling pubmed-94694572022-09-14 Sub-mucosal Dexamethasone for Post-operative Pain and Oedema Control in Lower Third Molar Surgery Virkar, Yogiraj B. Chawla, Jitendra Changmai, Arindom Kumar, Krishna Abhishek, Kumar Jawaid, Moazzam J Pharm Bioallied Sci Original Article BACKGROUND: Surgical excision of the problematic mandibular third molars causes substantial tissue damage and an inflammatory response. Discomfort and edema are common postoperative signs and symptoms caused by the latter. To find out whether dexamethasone may help with the edema and pain that come along with the surgical removal of impacted mandibular third molars, researchers have performed clinical studies. METHODS: Twenty individuals with bilaterally affected mandibular third molars who were scheduled for extraction participated in a prospective trial. At two separate sessions, teeth were raised and cut after buccal ostectomy. Since the surgical operation on the left foot, both patients were administered a mixture of 4 mg dexamethasone submucosal injection and antibiotics for 3 days. On the 1(st), 3(rd), and 7(th) postoperative days, edema and pain were assessed. RESULTS: At the 1(st), 3(rd), and 7(th) postoperative days, there was a clinically meaningful decrease in the level of edema and discomfort in both arms. CONCLUSIONS: The current report offers empirical proof that administering a 4 mg dexamethasone submucosal injection during surgery greatly reduced post-surgical edema and discomfort. Wolters Kluwer - Medknow 2022-07 2022-07-13 /pmc/articles/PMC9469457/ /pubmed/36110784 http://dx.doi.org/10.4103/jpbs.jpbs_8_22 Text en Copyright: © 2022 Journal of Pharmacy and Bioallied Sciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Virkar, Yogiraj B.
Chawla, Jitendra
Changmai, Arindom
Kumar, Krishna
Abhishek, Kumar
Jawaid, Moazzam
Sub-mucosal Dexamethasone for Post-operative Pain and Oedema Control in Lower Third Molar Surgery
title Sub-mucosal Dexamethasone for Post-operative Pain and Oedema Control in Lower Third Molar Surgery
title_full Sub-mucosal Dexamethasone for Post-operative Pain and Oedema Control in Lower Third Molar Surgery
title_fullStr Sub-mucosal Dexamethasone for Post-operative Pain and Oedema Control in Lower Third Molar Surgery
title_full_unstemmed Sub-mucosal Dexamethasone for Post-operative Pain and Oedema Control in Lower Third Molar Surgery
title_short Sub-mucosal Dexamethasone for Post-operative Pain and Oedema Control in Lower Third Molar Surgery
title_sort sub-mucosal dexamethasone for post-operative pain and oedema control in lower third molar surgery
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469457/
https://www.ncbi.nlm.nih.gov/pubmed/36110784
http://dx.doi.org/10.4103/jpbs.jpbs_8_22
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