Intratumor heterogeneity of driver mutations and TMB distribution in 30 early-stage LUAD patients with multiple lesions

BACKGROUND: Differentiating multiple pulmonary lesions as multiple primary lung cancer (MLC) or intra-pulmonary metastasis (IPM) is critical. Lung cancer also has a high genetic heterogeneity, which influenced the treatment strategy. Genetic information may aid in tracing lineage information on mult...

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Detalles Bibliográficos
Autores principales: Qiu, Yuan, Liu, Liping, Yang, Haihong, Chen, Hanzhang, Deng, Qiuhua, Xiao, Dakai, Lin, Yongping, Zhu, Changbin, Li, Weiwei, Shao, Di, Jiang, Wenxi, Wu, Kui, He, Jianxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469651/
https://www.ncbi.nlm.nih.gov/pubmed/36110964
http://dx.doi.org/10.3389/fonc.2022.952572

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