Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain

Although dormancy is thought to play a key role in the metastasis of breast tumor cells to the brain, our knowledge of the molecular mechanisms regulating disseminated tumour cell (DTC) dormancy in this organ is limited. Here, using serial intravital imaging of dormant and metastatic triple-negative...

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Detalles Bibliográficos
Autores principales: Dai, Jinxiang, Cimino, Patrick J., Gouin, Kenneth H., Grzelak, Candice A., Barrett, Alexander, Lim, Andrea R., Long, Annalyssa, Weaver, Stephanie, Saldin, Lindsey T., Uzamere, Aiyedun, Schulte, Vera, Clegg, Nigel, Pisarsky, Laura, Lyden, David, Bissell, Mina J., Knott, Simon, Welm, Alana L., Bielas, Jason H., Hansen, Kirk C., Winkler, Frank, Holland, Eric C., Ghajar, Cyrus M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469899/
https://www.ncbi.nlm.nih.gov/pubmed/35121993
http://dx.doi.org/10.1038/s43018-021-00297-3

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