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A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular response to etoposide-induced DNA damage

The Comet or single-cell gel electrophoresis assay is a highly sensitive method to measure cellular, nuclear genome damage. However, low throughput can limit its application for large-scale studies. To overcome these limitations, a 96-well CometChip platform was recently developed that increases thr...

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Detalles Bibliográficos
Autores principales: Li, Jianfeng, Beiser, Alison, Dey, Nupur B, Takeda, Shunichi, Saha, Liton Kumar, Hirota, Kouji, Parker, L Lynette, Carter, Mariah, Arrieta, Martha I, Sobol, Robert W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469923/
https://www.ncbi.nlm.nih.gov/pubmed/36110898
http://dx.doi.org/10.1093/nargab/lqac065