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Celda: a Bayesian model to perform co-clustering of genes into modules and cells into subpopulations using single-cell RNA-seq data
Single-cell RNA-seq (scRNA-seq) has emerged as a powerful technique to quantify gene expression in individual cells and to elucidate the molecular and cellular building blocks of complex tissues. We developed a novel Bayesian hierarchical model called Cellular Latent Dirichlet Allocation (Celda) to...
Autores principales: | Wang, Zhe, Yang, Shiyi, Koga, Yusuke, Corbett, Sean E, Shea, Conor V, Johnson, W Evan, Yajima, Masanao, Campbell, Joshua D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469931/ https://www.ncbi.nlm.nih.gov/pubmed/36110899 http://dx.doi.org/10.1093/nargab/lqac066 |
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