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Liver-specific overexpression of lipoprotein lipase improves glucose metabolism in high-fat diet-fed mice
The liver is the main organ that regulates lipid and glucose metabolism. Ectopic lipid accumulation in the liver impairs insulin sensitivity and glucose metabolism. Lipoprotein lipase (LPL), mainly expressed in the adipose tissue and muscle, is a key enzyme that regulates lipid metabolism via the hy...
Autores principales: | Shimizu, Kahori, Nishimuta, Syogo, Fukumura, Yuri, Michinaga, Shotaro, Egusa, Yuka, Hase, Tomomi, Terada, Tomoyuki, Sakurai, Fuminori, Mizuguchi, Hiroyuki, Tomita, Koji, Nishinaka, Toru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469954/ https://www.ncbi.nlm.nih.gov/pubmed/36099304 http://dx.doi.org/10.1371/journal.pone.0274297 |
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