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Wnt5a–Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions

Lung branching morphogenesis requires reciprocal interactions between the epithelium and mesenchyme. How the lung branches are generated at a defined location and projected toward a specific direction remains a major unresolved issue. In this study, we investigated the function of Wnt signaling in l...

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Detalles Bibliográficos
Autores principales: Zhang, Kuan, Yao, Erica, Chuang, Ethan, Chen, Biao, Chuang, Evelyn Y., Volk, Regan F., Hofmann, Katherine L., Zaro, Balyn, Chuang, Pao-Tien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9469998/
https://www.ncbi.nlm.nih.gov/pubmed/36026468
http://dx.doi.org/10.1371/journal.pbio.3001759