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Exploring pain interference with motor skill learning in humans: A systematic review

Motor learning underpins successful motor skill acquisition. Although it is well known that pain changes the way we move, it’s impact on motor learning is less clear. The aim of this systematic review was to synthesize evidence on the impact of experimental and clinical pain on task performance and...

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Autores principales: Matthews, David, Cancino, Edith Elgueta, Falla, Deborah, Khatibi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470002/
https://www.ncbi.nlm.nih.gov/pubmed/36099284
http://dx.doi.org/10.1371/journal.pone.0274403
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author Matthews, David
Cancino, Edith Elgueta
Falla, Deborah
Khatibi, Ali
author_facet Matthews, David
Cancino, Edith Elgueta
Falla, Deborah
Khatibi, Ali
author_sort Matthews, David
collection PubMed
description Motor learning underpins successful motor skill acquisition. Although it is well known that pain changes the way we move, it’s impact on motor learning is less clear. The aim of this systematic review was to synthesize evidence on the impact of experimental and clinical pain on task performance and activity-dependent plasticity measures across learning and explore these findings in relation to different pain and motor learning paradigms. Five databases were searched: Web of Science, Scopus, MEDLINE, Embase and CINAHL. Two reviewers independently screened the studies, extracted data, and assessed risk of bias using the Cochrane ROB2 and ROBIN-I. The overall strength of evidence was rated using the GRADE guidelines. Due to the heterogeneity of study methodologies a narrative synthesis was employed. Twenty studies were included in the review: fifteen experimental pain and five clinical pain studies, covering multiple motor paradigms. GRADE scores for all outcome measures suggested limited confidence in the reported effect for experimental pain and clinical pain, on motor learning. There was no impact of pain on any of the task performance measures following acquisition except for ‘accuracy’ during a tongue protrusion visuomotor task and ‘timing of errors’ during a motor adaptation locomotion task. Task performance measures at retention, and activity dependent measures at both acquisition and retention showed conflicting results. This review delivers a detailed synthesis of research studies exploring the impact of pain on motor learning. This is despite the challenges provided by the heterogeneity of motor learning paradigms, outcome measures and pain paradigms employed in these studies. The results highlight important questions for further research with the goal of strengthening the confidence of findings in this area.
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spelling pubmed-94700022022-09-14 Exploring pain interference with motor skill learning in humans: A systematic review Matthews, David Cancino, Edith Elgueta Falla, Deborah Khatibi, Ali PLoS One Research Article Motor learning underpins successful motor skill acquisition. Although it is well known that pain changes the way we move, it’s impact on motor learning is less clear. The aim of this systematic review was to synthesize evidence on the impact of experimental and clinical pain on task performance and activity-dependent plasticity measures across learning and explore these findings in relation to different pain and motor learning paradigms. Five databases were searched: Web of Science, Scopus, MEDLINE, Embase and CINAHL. Two reviewers independently screened the studies, extracted data, and assessed risk of bias using the Cochrane ROB2 and ROBIN-I. The overall strength of evidence was rated using the GRADE guidelines. Due to the heterogeneity of study methodologies a narrative synthesis was employed. Twenty studies were included in the review: fifteen experimental pain and five clinical pain studies, covering multiple motor paradigms. GRADE scores for all outcome measures suggested limited confidence in the reported effect for experimental pain and clinical pain, on motor learning. There was no impact of pain on any of the task performance measures following acquisition except for ‘accuracy’ during a tongue protrusion visuomotor task and ‘timing of errors’ during a motor adaptation locomotion task. Task performance measures at retention, and activity dependent measures at both acquisition and retention showed conflicting results. This review delivers a detailed synthesis of research studies exploring the impact of pain on motor learning. This is despite the challenges provided by the heterogeneity of motor learning paradigms, outcome measures and pain paradigms employed in these studies. The results highlight important questions for further research with the goal of strengthening the confidence of findings in this area. Public Library of Science 2022-09-13 /pmc/articles/PMC9470002/ /pubmed/36099284 http://dx.doi.org/10.1371/journal.pone.0274403 Text en © 2022 Matthews et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Matthews, David
Cancino, Edith Elgueta
Falla, Deborah
Khatibi, Ali
Exploring pain interference with motor skill learning in humans: A systematic review
title Exploring pain interference with motor skill learning in humans: A systematic review
title_full Exploring pain interference with motor skill learning in humans: A systematic review
title_fullStr Exploring pain interference with motor skill learning in humans: A systematic review
title_full_unstemmed Exploring pain interference with motor skill learning in humans: A systematic review
title_short Exploring pain interference with motor skill learning in humans: A systematic review
title_sort exploring pain interference with motor skill learning in humans: a systematic review
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470002/
https://www.ncbi.nlm.nih.gov/pubmed/36099284
http://dx.doi.org/10.1371/journal.pone.0274403
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