Glycopeptoid nanospheres: glycosylation-induced coacervation of poly(sarcosine)

Conjugation of maltopentaose to water-soluble homo-poly(sarcosine) induced self-association and formed nanospheres (−150 nm) in water although homo-poly(sarcosine) was water-soluble and did not form any aggregates. Fluorescent probe experiments showed that the spheres were non-ionic glycopeptoid coa...

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Detalles Bibliográficos
Autores principales: Okuno, Yota, Nishimura, Tomoki, Sasaki, Yoshihiro, Akiyoshi, Kazunari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470024/
https://www.ncbi.nlm.nih.gov/pubmed/36133351
http://dx.doi.org/10.1039/d2na00218c
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author Okuno, Yota
Nishimura, Tomoki
Sasaki, Yoshihiro
Akiyoshi, Kazunari
author_facet Okuno, Yota
Nishimura, Tomoki
Sasaki, Yoshihiro
Akiyoshi, Kazunari
author_sort Okuno, Yota
collection PubMed
description Conjugation of maltopentaose to water-soluble homo-poly(sarcosine) induced self-association and formed nanospheres (−150 nm) in water although homo-poly(sarcosine) was water-soluble and did not form any aggregates. Fluorescent probe experiments showed that the spheres were non-ionic glycopeptoid coacervate-like particles with both hydrophobic and hydrophilic domains inside.
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spelling pubmed-94700242022-09-20 Glycopeptoid nanospheres: glycosylation-induced coacervation of poly(sarcosine) Okuno, Yota Nishimura, Tomoki Sasaki, Yoshihiro Akiyoshi, Kazunari Nanoscale Adv Chemistry Conjugation of maltopentaose to water-soluble homo-poly(sarcosine) induced self-association and formed nanospheres (−150 nm) in water although homo-poly(sarcosine) was water-soluble and did not form any aggregates. Fluorescent probe experiments showed that the spheres were non-ionic glycopeptoid coacervate-like particles with both hydrophobic and hydrophilic domains inside. RSC 2022-06-27 /pmc/articles/PMC9470024/ /pubmed/36133351 http://dx.doi.org/10.1039/d2na00218c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Okuno, Yota
Nishimura, Tomoki
Sasaki, Yoshihiro
Akiyoshi, Kazunari
Glycopeptoid nanospheres: glycosylation-induced coacervation of poly(sarcosine)
title Glycopeptoid nanospheres: glycosylation-induced coacervation of poly(sarcosine)
title_full Glycopeptoid nanospheres: glycosylation-induced coacervation of poly(sarcosine)
title_fullStr Glycopeptoid nanospheres: glycosylation-induced coacervation of poly(sarcosine)
title_full_unstemmed Glycopeptoid nanospheres: glycosylation-induced coacervation of poly(sarcosine)
title_short Glycopeptoid nanospheres: glycosylation-induced coacervation of poly(sarcosine)
title_sort glycopeptoid nanospheres: glycosylation-induced coacervation of poly(sarcosine)
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470024/
https://www.ncbi.nlm.nih.gov/pubmed/36133351
http://dx.doi.org/10.1039/d2na00218c
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AT sasakiyoshihiro glycopeptoidnanospheresglycosylationinducedcoacervationofpolysarcosine
AT akiyoshikazunari glycopeptoidnanospheresglycosylationinducedcoacervationofpolysarcosine

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