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Irisin Ameliorates Oxidative Stress-Induced Injury in Pancreatic Beta-Cells by Inhibiting Txnip and Inducing Stat3-Trx2 Pathway Activation

Lipotoxicity can lead to beta-cell dysfunction and apoptosis because it induces oxidative stress. Recent studies have found that Irisin prevents pancreatic beta-cell dysfunction induced by palmitic acid (PA). However, an association between the protection against oxidative stress conferred by Irisin...

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Detalles Bibliográficos
Autores principales: Liu, Chongxiao, Zhou, Jianhua, Xu, Yanhong, Gong, Sa, Zhu, Yi, Zhang, Hongli, Dong, Yan, Zhao, Bingxia, Li, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470320/
https://www.ncbi.nlm.nih.gov/pubmed/36111165
http://dx.doi.org/10.1155/2022/4674215