Cargando…
Irisin Ameliorates Oxidative Stress-Induced Injury in Pancreatic Beta-Cells by Inhibiting Txnip and Inducing Stat3-Trx2 Pathway Activation
Lipotoxicity can lead to beta-cell dysfunction and apoptosis because it induces oxidative stress. Recent studies have found that Irisin prevents pancreatic beta-cell dysfunction induced by palmitic acid (PA). However, an association between the protection against oxidative stress conferred by Irisin...
Autores principales: | Liu, Chongxiao, Zhou, Jianhua, Xu, Yanhong, Gong, Sa, Zhu, Yi, Zhang, Hongli, Dong, Yan, Zhao, Bingxia, Li, Xiaohua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470320/ https://www.ncbi.nlm.nih.gov/pubmed/36111165 http://dx.doi.org/10.1155/2022/4674215 |
Ejemplares similares
-
Irisin suppresses pancreatic β cell pyroptosis in T2DM by inhibiting the NLRP3-GSDMD pathway and activating the Nrf2-TrX/TXNIP signaling axis
por: Li, Tianrong, et al.
Publicado: (2023) -
FOXO1 Overexpression Attenuates Tubulointerstitial Fibrosis and Apoptosis in Diabetic Kidneys by Ameliorating Oxidative Injury via TXNIP-TRX
por: Ji, Linlin, et al.
Publicado: (2019) -
Enhanced Oxidative DNA-Damage in Peritoneal Dialysis Patients via the TXNIP/TRX Axis
por: Oberacker, Tina, et al.
Publicado: (2022) -
Ceramide induces the apoptosis of non-small cell lung cancer cells through the Txnip/Trx1 complex
por: Shi, Yining, et al.
Publicado: (2021) -
TXNIP/TRX/NF-κB and MAPK/NF-κB pathways involved in the cardiotoxicity induced by Venenum Bufonis in rats
por: Bi, Qi-rui, et al.
Publicado: (2016)