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Limb-Bud and Heart (LBH) Upregulation in Cardiomyocytes under Hypoxia Promotes the Activation of Cardiac Fibroblasts via Exosome Secretion

The activation of cardiac fibroblasts (CFs) after myocardial infarction (MI) is essential for post-MI infarct healing, during which the regulation of transforming growth factor beta1 (TGF-β1) signaling is predominant. We have demonstrated that TGF-β1-mediated upregulation of LBH contributes to post-...

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Detalles Bibliográficos
Autores principales: Xu, Yuling, Wu, Anbiao, Chen, Jingyang, Song, Xudong, Chen, Minsheng, Liu, Qicai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470350/
https://www.ncbi.nlm.nih.gov/pubmed/36110098
http://dx.doi.org/10.1155/2022/8939449