Fatty acid metabolism in aggressive B-cell lymphoma is inhibited by tetraspanin CD37

The importance of fatty acid (FA) metabolism in cancer is well-established, yet the mechanisms underlying metabolic reprogramming remain elusive. Here, we identify tetraspanin CD37, a prognostic marker for aggressive B-cell lymphoma, as essential membrane-localized inhibitor of FA metabolism. Deleti...

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Detalles Bibliográficos
Autores principales: Peeters, Rens, Cuenca-Escalona, Jorge, Zaal, Esther A., Hoekstra, Anna T., Balvert, Anouk C. G., Vidal-Manrique, Marcos, Blomberg, Niek, van Deventer, Sjoerd J., Stienstra, Rinke, Jellusova, Julia, Giera, Martin, Hannibal, Luciana, Spiekerkoetter, Ute, ter Beest, Martin, Berkers, Celia R., van Spriel, Annemiek B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470561/
https://www.ncbi.nlm.nih.gov/pubmed/36100608
http://dx.doi.org/10.1038/s41467-022-33138-7

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