Life of double minutes: generation, maintenance, and elimination

Advances in genome sequencing have revealed a type of extrachromosomal DNA, historically named double minutes (also referred to as ecDNA), to be common in a wide range of cancer types, but not in healthy tissues. These cancer-associated circular DNA molecules contain one or a few genes that are ampl...

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Detalles Bibliográficos
Autores principales: Ilić, Mila, Zaalberg, Irene C., Raaijmakers, Jonne A., Medema, René H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470669/
https://www.ncbi.nlm.nih.gov/pubmed/35487993
http://dx.doi.org/10.1007/s00412-022-00773-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470669/
https://www.ncbi.nlm.nih.gov/pubmed/35487993
http://dx.doi.org/10.1007/s00412-022-00773-4

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